Results 91 to 100 of about 165,486 (356)

Chromatin status and transcription factor binding to gonadotropin promoters in gonadotrope cell lines. [PDF]

, 2017
BackgroundProper expression of key reproductive hormones from gonadotrope cells of the pituitary is required for pubertal onset and reproduction. To further our understanding of the molecular events taking place during embryonic development, leading to ...
Brayman, Melissa J, Hoffmann, Hanne M, Iyer, Anita K, Mellon, Pamela L, Ngo, Cindy, Sunshine, Mary Jean, Xie, Huimin   +6 more
core   +3 more sources

The Effects of Dietary Wheat and Corn Glutens on the Histopathological and Immunohistochemical Structure of the Ovarian Tissue and Serum and Ovarian Tissue LH and FSH Levels and Lipid Profiles in Rats [PDF]

, 2022
Halit İmik, Kübra Asena Terim Kapakin, Özlem Karabulutlu, Recep Gümüş, Selim Çomaklı, Mustafa Özkaraca   +5 more
openalex   +1 more source

The mitochondrial DNA copy number and ovary‐related reproductive disorders: A bidirectional two‐sample Mendelian randomization study

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.
Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng, Xiao Han, Congquan Wu, Qiaowen Lu, Shujun Gao   +4 more
wiley   +1 more source

SIRT1: A likely key for future therapeutic strategies for pain management

Pharmacological Research
Sirtuin 1 (SIRT1), a NAD+ -dependent histone deacetylase, plays a crucial role in mitigating oxidative stress, regulating inflammation, and maintaining mitochondrial function. Reduced SIRT1 activity has been linked to elevated pro-inflammatory cytokines,
Sara Ilari, Saverio Nucera, Lucia Carmela Passacatini, Rosamaria Caminiti, Valeria Mazza, Roberta Macrì, Maria Serra, Federica Scarano, Valentina Malafoglia, Ernesto Palma, Francesca Oppedisano, Jessica Maiuolo, Carlo Tomino, Vincenzo Mollace, Carolina Muscoli   +14 more
doaj   +1 more source

Optimizing outcomes in intrauterine insemination: A narrative synthesis of two decades of clinical research (2000–2024)

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Intrauterine insemination (IUI) is a widely used first‐line fertility treatment, yet its success rates vary considerably. This review synthesizes evidence from peer‐reviewed studies published between 2000 and 2024, including randomized controlled trials, cohort and case–control studies, as well as systematic and narrative reviews identified ...
Kasuni Akalanka
wiley   +1 more source

The potential effect of natural antioxidants on endothelial dysfunction associated with arterial hypertension

Frontiers in Cardiovascular Medicine
Arterial hypertension represents a leading cause of cardiovascular morbidity and mortality worldwide, and the identification of effective solutions for treating the early stages of elevated blood pressure (BP) is still a relevant issue for cardiovascular
Rosamaria Caminiti, Cristina Carresi, Rocco Mollace, Rocco Mollace, Roberta Macrì, Federica Scarano, Francesca Oppedisano, Jessica Maiuolo, Maria Serra, Stefano Ruga, Saverio Nucera, Annamaria Tavernese, Micaela Gliozzi, Vincenzo Musolino, Ernesto Palma, Carolina Muscoli, Carolina Muscoli, Speranza Rubattu, Speranza Rubattu, Maurizio Volterrani, Massimo Federici, Massimo Volpe, Vincenzo Mollace, Vincenzo Mollace   +23 more
doaj   +1 more source

Perturbations in Lineage Specification of Granulosa and Theca Cells May Alter Corpus Luteum Formation and Function [PDF]

, 2019
Anovulation is a major cause of infertility, and it is the major leading reproductive disorder in mammalian females. Without ovulation, an oocyte is not released from the ovarian follicle to be fertilized and a corpus luteum is not formed.
Abedel-Majed, Mohamed A., Cupp, Andrea S., Davis, John S., Romereim, Sarah M.   +3 more
core   +1 more source

Pharmacogenetics of FSH Action in the Female

Frontiers in Endocrinology, 2019
The purpose of a pharmacogenomic approach is to tailor treatment on the basis of an individual human genotype. This strategy is becoming increasingly common in medicine, and important results have been obtained in oncologic and antimicrobial therapies.
Alessandro Conforti, Alberto Vaiarelli, Danilo Cimadomo, Francesca Bagnulo, Stefania Peluso, Luigi Carbone, Francesca Di Rella, Giuseppe De Placido, Filippo Maria Ubaldi, Ilpo Huhtaniemi, Carlo Alviggi, Carlo Alviggi   +11 more
openaire   +5 more sources

Luteal phase stimulation versus follicular phase stimulation in poor ovarian responders: A systematic review and a meta‐analysis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Poor ovarian response (POR) complicates a substantial proportion of in vitro fertilization (IVF) cycles, frequently causing cycle cancellation and suboptimal reproductive outcomes. Conventional follicular‐phase ovarian stimulation (FPOS) protocols often yield limited results, prompting the evaluation of alternative strategies such ...
Vittorio Agrifoglio, Antonio D'Amato, Mariano Catello Di Donna, Marika Marino, Antonio Simone Laganà, Renato Venezia, Davide Vinci, Gaetano Riemma, Andrea Etrusco   +8 more
wiley   +1 more source

Targeting leptin/CCL3-CCL4 axes in NAFLD/MAFLD: A novel role for BPF in counteracting thalamic inflammation and white matter degeneration

Pharmacological Research
Non-alcoholic fatty liver disease (NAFLD), redefined as Metabolic Associated Fatty Liver Disease (MAFLD), is characterized by an extensive multi-organ involvement.
Antonio Cardamone, Anna Rita Coppoletta, Roberta Macrì, Saverio Nucera, Stefano Ruga, Federica Scarano, Rocco Mollace, Annachiara Mollace, Samantha Maurotti, Edoardo Micotti, Cristina Carresi, Vincenzo Musolino, Micaela Gliozzi, Vincenzo Mollace   +13 more
doaj   +1 more source