Results 21 to 30 of about 1,388,477 (251)

FSH-R Human Early Male Genital Tract, Testicular Tumors and Sperm: Its Involvement in Testicular Disorders

Life, 2020
The follicle-stimulating hormone receptor (FSH-R) expression was always considered human gonad-specific. The receptor has also been newly detected in extragonadal tissues.
Salvatore Panza, Francesca Giordano, Daniela De Rose, Maria Luisa Panno, Francesca De Amicis, Marta Santoro, Rocco Malivindi, Vittoria Rago, Saveria Aquila   +8 more
doaj   +1 more source

A comprehensive curated resource for follicle stimulating hormone signaling

BMC Research Notes, 2011
Background Follicle stimulating hormone (FSH) is an important hormone responsible for growth, maturation and function of the human reproductive system. FSH regulates the synthesis of steroid hormones such as estrogen and progesterone, proliferation and ...
Sharma Jyoti, Raju Rajesh, Dwivedi Sutopa B, Palapetta Shyam, Ambekar Aditi, Telikicherla Deepthi, Prasad TS Keshava, Ramachandra YL, Mohan S Sujatha, Maharudraiah Jagadeesha, Mukherjee Srabani, Pandey Akhilesh   +11 more
doaj   +1 more source

Effect of FSH on testicular morphology and spermatogenesis in gonadotrophin-deficient hypogonadal mice lacking androgen receptors [PDF]

, 2010
Follicle stimulating hormone (FSH) and androgen act to stimulate and maintain spermatogenesis. FSH acts directly on the Sertoli cells to stimulate germ cell number and acts indirectly to increase androgen production by the Leydig cells.
Abel, M.H., Verhoeven, G., De Gendt, K., Monteiro, A., O'Shaughnessy, P.J.   +4 more
core   +1 more source

Characterization of Constitutively Activating Eel Follicle-Stimulating Hormone Receptor

Journal of Animal Reproduction and Biotechnology, 2019
This study aimed to investigate the function of the constitutively activating mutation D540G on eel FSHR activity by in vitro functional studies. Site-directed mutagenesis was carried out to generate the D-to-G mutation at position 540 of the pcDNA3-eel ...
Jeong-Soo Kim, Munkhzaya Byambaragchaa, Kwan-Sik Min   +2 more
doaj   +1 more source

Effects of FSH on testicular mRNA transcript levels in the hypogonadal mouse [PDF]

, 2009
Follicle stimulating hormone (FSH) acts through the Sertoli cell to ensure normal testicular development and function. To identify transcriptional mechanisms through which FSH acts in the testis we have treated gonadotrophin-deficient hypogonadal (hpg ...
Abel, M.H., Lee, S., Charlton, H.M., O'Shaughnessy, P.J., Baban, D.   +4 more
core   +1 more source

Luteinizing hormone-like and follicle-stimulating hormone-like activities of equine chorionic gonadotropin β-subunit mutants in cells expressing rat luteinizing hormone/chorionic gonadotropin receptor and rat follicle-stimulating hormone receptor

Animal Cells and Systems, 2021
To identify the specific region of eCG involved in FSH-like activity, the following mutant expression vectors were constructed targeting the amino acid residues 102–104 of the eCG β-subunit: single mutants, eCGβV102G/α, eCGβF103P/α, and eCGβR104K/α ...
Munkhzaya Byambaragchaa, Ayoung Park, So-Jin Gil, Hae-Won Lee, Yun-Jeong Ko, Seung-Hee Choi, Myung-Hwa Kang, Kwan-Sik Min   +7 more
doaj   +1 more source

Testicular development in mice lacking receptors for follicle stimulating hormone and androgen [PDF]

, 2012
Post-natal testicular development is dependent on gonadotrophin and androgen stimulation. Follicle stimulating hormone (FSH) acts through receptors (FSHR) on the Sertoli cell to stimulate spermatogenesis while androgens promote testis growth through ...
Abel, M., Ana Monteiro, Abel Margaret, Margaret Abel, Peter J. O’Shaughnessy (171628), O’Shaughnessy Peter J., Monteiro, A., O'Shaughnessy, P.J., Ana Monteiro (171632), Peter J O'Shaughnessy, Margaret Abel (171636), Monteiro Ana   +11 more
core   +2 more sources

FSH stimulates lipid biosynthesis in chicken adipose tissue by upregulating the expression of its receptor FSHR

Journal of Lipid Research, 2012
Transcripts and protein for follicle-stimulating hormone receptor (FSHR) were demonstrated in abdominal adipose tissue of female chickens. There was no expression of the Fsh gene, but FSH and FSHR colocalized, suggesting that FSH was receptor bound ...
Huanxian Cui, Guiping Zhao, Ranran Liu, Maiqing Zheng, Jilan Chen, Jie Wen   +5 more
doaj   +1 more source

Spermatogenesis and sertoli cell activity in mice lacking Sertoli cell receptors for follicle stimulating hormone and androgen [PDF]

, 2008
Spermatogenesis in the adult male depends on the action of FSH and androgen. Ablation of either hormone has deleterious effects on Sertoli cell function and the progression of germ cells through spermatogenesis.
Baker, P.J., Guillou, F., Abel, M.H., Verhoeven, G., De Gendt, K., Guillou, Florian Jean Louis, Charlton, H.M., Monteiro, A., O'Shaughnessy, P.J.   +8 more
core   +1 more source

Follicle-Stimulating Hormone Increases the Risk of Postmenopausal Osteoporosis by Stimulating Osteoclast Differentiation. [PDF]

PLoS ONE, 2015
The objectives of this study were to observe the changes in follicle-stimulating hormone (FSH) and bone mineral density (BMD) in postmenopausal women, to research the relationship between FSH and postmenopausal osteoporosis, and to observe the effects of
Jie Wang, Wenwen Zhang, Chunxiao Yu, Xu Zhang, Haiqing Zhang, Qingbo Guan, Jiajun Zhao, Jin Xu   +7 more
doaj   +1 more source