Results 41 to 50 of about 3,023 (153)

Pharmacological Programming of Endosomal Signaling Activated by Small Molecule Ligands of the Follicle Stimulating Hormone Receptor

open access: yesFrontiers in Pharmacology, 2020
Follicle-stimulating hormone receptor (FSHR) is a G protein-coupled receptor (GPCR) with pivotal roles in reproduction. One key mechanism dictating the signal activity of GPCRs is membrane trafficking.
Silvia Sposini   +10 more
doaj   +1 more source

Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor

open access: yesNature Communications, 2023
Follicle stimulating hormone (FSH) is a glycoprotein hormone the functions of which are mediated by a G protein-coupled receptor, FSHR. Here, Duan et al.
Jia Duan   +14 more
doaj   +1 more source

Characterization of polymorphisms in the follicle-stimulating hormone receptor and insulin-like growth factor-1 genes and their association with fertility traits in Jawa-Brebes cows [PDF]

open access: yesVeterinary World, 2023
Background and Aim: The availability of fertility markers is crucial for maintaining, protecting, and improving the genetics of Jawa-Brebes (Jabres) cows. Follicle-stimulating hormone receptor (FSHR) and insulin-like growth factor-1 (IGF-1) play critical
Slamet Hartanto   +4 more
doaj   +1 more source

Follicle-Stimulating Hormone Induces Lipid Droplets via Gαi/o and β-Arrestin in an Endometrial Cancer Cell Line

open access: yesFrontiers in Endocrinology, 2022
Follicle-stimulating hormone (FSH) and its G protein-coupled receptor, FSHR, represents a paradigm for receptor signaling systems that activate multiple and complex pathways.
Niamh S. Sayers   +6 more
doaj   +1 more source

Distal regulatory elements are required for Fshr expression, in vivo [PDF]

open access: yesMolecular and Cellular Endocrinology, 2007
The gonadotropin follicle-stimulating hormone (FSH) is required for initiation and maintenance of normal gametogenesis and acts through a specific, cell-surface receptor (Fshr) present only on Sertoli and granulosa cells in the gonads. Despite extensive examination of the transcriptional mechanisms regulating Fshr, the sequences directing its ...
Brian P, Hermann   +3 more
openaire   +2 more sources

Immunohistochemical detection of follicle stimulating hormone receptor (FSHR) in neuroendocrine tumours [PDF]

open access: yes, 2013
Wstęp: Wiadomo, że ekspresja receptorów folitropiny (FSHR) występuje w gonadach i wywodzących się z gonad nowotworach. Ostatniowykazano ich obecność także w innych nowotworach endokrynnych, takich jak guzy nadnerczy i gruczolaki przysadki ...
Pawlikowski, Marek   +2 more
core   +1 more source

FSHR-1 and Innate Immunity

open access: yes, 2014
Innate immunity is critical for all organisms against microbial pathogens. It is the first line of defense that organisms possess and is used in the activation of adaptive immune response in mammalian vertebrates.
James Polek (10083274)
core   +1 more source

Molecular analysis of a mutated FSH receptor detected in a patient with spontaneous ovarian hyperstimulation syndrome. [PDF]

open access: yesPLoS ONE, 2013
Spontaneous ovarian hyperstimulation syndrome (sOHSS) is a rare event that may result from a FSH-producing pituitary adenoma (FSHoma), activating mutations of the FSH receptor (FSHR), and cross-reactivity of the FSHR to elevated hCG and TSH in the ...
Sayaka Uchida   +7 more
doaj   +1 more source

Novel FSH receptor mutation in a case of spontaneous ovarian hyperstimulation syndrome with successful pregnancy outcome

open access: yesJournal of Human Reproductive Sciences, 2015
The objective is to study the FSH receptor (FSHR) for mutations in a case of spontaneous ovarian hyperstimulation syndrome (sOHSS). This is a single case study and it examined patient who presented with spontaneous critical OHSS in early pregnancy and ...
Anahita R Chauhan   +5 more
doaj   +1 more source

Extragonadal FSHR Expression and Function—Is It Real? [PDF]

open access: yes, 2022
Expression of the follicle-stimulating hormone receptor (FSHR), besides gonadal tissues, has recently been detected in several extragonadal normal and tumorous tissues, including different types of primary and metastatic cancer and tumor vessel ...
Huhtaniemi Ilpo   +4 more
core   +1 more source

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