Results 21 to 30 of about 3,023 (153)
Biased Signaling and Allosteric Modulation at the FSHR [PDF]
Frontiers in Endocrinology, 2019 Knowledge on G protein-coupled receptor (GPCRs) structure and mechanism of activation has profoundly evolved over the past years. The way drugs targeting this family of receptors are discovered and used has also changed.
Flavie Landomiel +10 more
doaj +6 more sources
Comment on “Atlas of Fshr Expression From Novel Reporter Mice” [PDF]
EndocrinologyIn recent years, there have been controversial claims of extragonadal effects of follicle-stimulating hormone (FSH). A paper by Chen et al (1) recently published in eLife further muddies the waters, though its intent was to provide clarity.
Casarini, Livio +17 more
openaire +3 more sources
Journal of Lipid Research, 2012 Transcripts and protein for follicle-stimulating hormone receptor (FSHR) were demonstrated in abdominal adipose tissue of female chickens. There was no expression of the Fsh gene, but FSH and FSHR colocalized, suggesting that FSH was receptor bound ...
Jie Wen, Guiping Zhao, Maiqing Zheng
exaly +3 more sources
Follicle-Stimulating Hormone Receptor (FSHR): A Promising Tool in Oncology?
Molecular Diagnosis & Therapy, 2016 The cellular pathway of follicle-stimulating hormone (FSH) and its receptor (FSHR) is typically involved in reproduction in mammals. In humans, the FSHR is normally found in cells of the testis and the ovary, while it is scarcely expressed in other normal tissues.
Papadimitriou, Konstantinos +6 more
openaire +4 more sources
Indian Journal of Endocrinology and Metabolism, 2021 Background: Polycystic ovarian syndrome (PCOS) is typically characterized by a spectrum of manifestations that include menstrual irregularities, anovulation, cysts, hyperandrogenic features like hirsutism, acne, alopecia, and various metabolic ...
Balaji Ramanathan +2 more
doaj +1 more source
Акушерство, гинекология и репродукция, 2023 Introduction. Infertility is a highly fatal reproductive system disorder that affects the ability of a couple to reproduce. Over the past decades, a drastic uplift has been recorded in infertility cases among males ranging from 20 to 70 % indicating ...
N. A. Oohayyed +5 more
doaj +1 more source
Intra-cellular VHH targeting the FSHR and LHR
Intracellular variable fragments from heavy-chain antibody from camelids (intra-VHH) have beensuccessfully used as chaperones to solve the 3D structure of active G protein-coupled receptors(GPCRs) bound to their cognate transducers. They may also provide a better understanding onthe relationships between receptor conformation and signalling activity ...
Crépieux, Pascale
core +6 more sources
Journal of the Indonesian Tropical Animal Agriculture, 2023 The objective of this study was to discover and identify the effect of SNP of follicle-stimulating hormone receptor (FSHR) gen on prolific traits in Kejobong (KJ) and Etawah grade (EG) doe.
E. T. Setiatin +4 more
doaj +1 more source
Polymorphisms in FSHR and GDF9 loci and their associations with litter size in Zel sheep [PDF]
مجله بیوتکنولوژی کشاورزی, 2014 Follicle stimulating hormone receptor (FSHR) and growth differentiation factor 9 (GDF9) both are the most important proteins that affect reproduction process in mammalian.
Nouraldin Moradi +3 more
doaj +1 more source
Atenolol increases dental mineralization in male offspring of treated hypertensive rats and normotensive rats [PDF]
Brazilian Oral Research, 2020 This study evaluates how atenolol affects dental mineralization in offspring of female spontaneously hypertensive rats (fSHR) and normotensive Wistar rats (fW). fSHR and fW were treated with atenolol (100 mg/Kg/day, orally) during pregnancy and lactation.
Gracieli Prado ELIAS +4 more
doaj +1 more source