Granulosa cell apoptosis in the ovarian follicle - a changing view [PDF]
Recent studies challenge the previous view that apoptosis within the granulosa cells of the maturing ovarian follicle is a reflection of aging and consequently a marker for poor quality of the contained oocyte.
Arun Dharmarajan+6 more
core +3 more sources
Small Molecule Follicle-Stimulating Hormone Receptor Agonists and Antagonists
The follicle-stimulating hormone receptor (FSHR) has been targeted therapeutically for decades, due to its pivotal role in reproduction. To date, only purified and recombinant/biosimilar FSH have been used to target FSHR in assisted reproduction, with ...
Ross C. Anderson+3 more
doaj +1 more source
Mechanism of action of gonadotrophins in the bovine ovary and its participation in cystic ovarian disease [PDF]
Las gonadotrofinas son esenciales para la función ovárica del bovino actuando, a través de la interacción con sus receptores, en la regulación del crecimiento y la maduración folicular así como en la esteroidogénesis.
Amweg, Ayelen Noelia+5 more
core +2 more sources
AreFSHRpolymorphisms risk factors to premature ovarian insufficiency?
Premature ovarian insufficiency (POI) is an ovarian dysfunction characterized by increased FSH levels and amenorrhea before 40 years old. In recent years, the search for genetic causes of POI intensified and studies have been published relating the presence of mutations and polymorphisms in genes associated with development, recruitment and oocyte ...
Bianca Bianco+4 more
openaire +3 more sources
Development and application of a bioassay for follicle-stimulating hormone : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Physiology at Massey University [PDF]
Follicle-stimulating hormone (FSH) is involved in the regulation and maintenance of vital reproductive processes, such as gametogenesis, follicular development and ovulation.
Young, Wayne
core
Spermatogenesis and sertoli cell activity in mice lacking Sertoli cell receptors for follicle stimulating hormone and androgen [PDF]
Spermatogenesis in the adult male depends on the action of FSH and androgen. Ablation of either hormone has deleterious effects on Sertoli cell function and the progression of germ cells through spermatogenesis.
A. Monteiro+63 more
core +2 more sources
Follicle-stimulating hormone receptor (FSHR), which is expressed only on Sertoli cells and plays a key role in spermatogenesis, has been paid attention for its potential in male contraception vaccine research and development.
Cheng Xu+9 more
doaj +1 more source
Characterization of gonadotropin receptors Fshr and Lhr in Japanese medaka, Oryzias latipes
Reproduction in vertebrates is controlled by the brain-pituitary-gonad axis, where the two gonadotropins follicle-stimulating hormone (Fsh) and luteinizing hormone (Lh) play vital parts by activating their cognate receptors in the gonads. The main purpose of this work was to study intra- and interspecies ligand promiscuity of teleost gonadotropin ...
Susann Burow+9 more
openaire +4 more sources
Assessment of FSHR, AMH, and AMHRII variants in women with polycystic ovary syndrome [PDF]
Polycystic ovary syndrome (PCOS) is the most frequentendocrinopathy present in 6–15 % of reproductive-agewomen [1]. It is a heterogenous syndrome [2, 3] andaccording to the Rotterdam Criteria [4], PCOS is recog-nized in women who have two of three symptoms: chronicamenorrhea, clinical or biochemical hyperandrogenism andthe ovarian morphology of PCO in ...
Katarzyna Jarząbek+6 more
openaire +4 more sources
Pathogen Response Genes Mediate Caenorhabditis elegans Innate Immunity
Innate immunity is crucial in the response and defense against pathogens for invertebrates and vertebrates alike. The soil nematode Caenorhabditis elegans is a useful model to study the eukaryotic innate immune response to microbial pathogenesis.
Anthony, Hannah L.
core