Results 81 to 90 of about 3,023 (153)

Non-synonymous SNPs of FSHR at positions 307 (rs6165) and 680 (rs6166) in Chinese women.

, 2012
FSHR (rs6165), AA: 307Thr/Thr; GG: 307Ala/Ala; GA: 307Ala/Thr.FSHR (rs6166), AA: 680Asn/Asn; GG: 680Ser/Ser; GA: 680Ser/Asn.
Yun-Shien Lee (90565), Tzu-Hao Wang (14039), Hsien-Da Huang (1748), Hsien-Ming Wu (123280), Bi-Hwa Cheng (123284), Chih-Feng Yen (123288), Pi-Yueh Chang (123293), Hsin-Shih Wang (8802), Angel Chao (123295)   +8 more
core   +1 more source

The preparation and application of N-terminal 57 amino acid protein of the follicle-stimulating hormone receptor as a candidate male contraceptive vaccine

Asian Journal of Andrology, 2014
Follicle-stimulating hormone receptor (FSHR), which is expressed only on Sertoli cells and plays a key role in spermatogenesis, has been paid attention for its potential in male contraception vaccine research and development.
Cheng Xu, Ying-Chun Li, Hua Yang, Yan Long, Min-Jian Chen, Yu-Feng Qin, Yan-Kai Xia, Ling Song, Ai-Hua Gu, Xin-Ru Wang   +9 more
doaj   +1 more source

The evolving role of immunotherapy in ovarian cancer

Cancer, Volume 132, Issue 18, 15 September 2026.
Abstract Ovarian cancer remains a major cause of gynecologic cancer mortality; and, although immune checkpoint inhibitors have transformed treatment in other solid tumors, their activity in ovarian cancer has been limited by tumor heterogeneity, an immunosuppressive tumor microenvironment, and the lack of robust predictive biomarkers.
Ana Carolina Veneziani, Laura Venegas, Amit M. Oza   +2 more
wiley   +1 more source

Hormonal Therapy Before Micro‐TESE in Men With Nonobstructive Azoospermia: A Negative Answer to an Overly Broad Question

Andrology, EarlyView.
Sandro C. Esteves, Arnold P. P. Achermann, Ricardo Miyaoka, Cassio L. Z. Riccetto, Adriano Fregonesi   +4 more
wiley   +1 more source

A uterine‐centric view of reproductive senescence: Genetic insights into late‐life performance in laying hens

iMetaOmics, Volume 3, Issue 3, September 2026.
This study identifies uterus weight as a heritable (h2 = 0.45) intermediate phenotype that independently associates with late‐life egg production and eggshell quality in aged laying hens. Genome‐wide association study (GWAS) reveals a genome‐wide significant locus on chromosome 3 and suggestive loci on chromosome 11 for uterus weight, mediation ...
Junnan Zhang, Mingyue Gao, Ronglang Cai, Xinwei Jiang, Boxuan Zhang, Zhaojie Li, Ning Yang, Congjiao Sun   +7 more
wiley   +1 more source

Author's Response: Can Hormonal Therapy Improve the Outcomes of mTESE in Patients with Nonobstructive Azoospermia?

Andrology, EarlyView.
M. Anfosso, M. Schubert, JF. Cremers, S. Kliesch, M. Zitzmann, S. Bier   +5 more
wiley   +1 more source

Growth Hormone Reverses Cisplatin‐Induced Ovarian Reserve Depletion in Mice: Transcriptomic Elucidation of Mitochondrial Metabolic Reprogramming and Protein Synthesis Regulation

FASEB BioAdvances, Volume 8, Issue 9, September 2026.
This study investigated the effects of different doses of growth hormone (GH) on cisplatin (CDDP)‐induced ovarian injury and the underlying mechanisms in female Kunming mice. First, a diminished ovarian reserve (DOR) model was established by intraperitoneal injection of 1.5 mg/kg CDDP for 7 consecutive days.
Tianhong Huang, Niu Wang, Dongsheng Xiong, Yanan Zhang, Jiajing Wei, Furui Chen, Yu Qiu, Fangyi Long, Qianwen Luo, Jesse Li‐Ling, Yan Gong   +10 more
wiley   +1 more source

Targeted destruction of follicle stimulating hormone receptor-positive cancer cells in vitro and in vivo by a lytic peptide Phor21-FSHβ conjugate

Molecular Medicine
Background Extragonadal follicle-stimulating hormone (FSH) receptor (FSHR) expression in various cancers and their endothelial vessel cells has highlighted novel opportunities for targeted FSHR therapy.
Nafis A. Rahman, Marcin Chrusciel, Donata Ponikwicka-Tyszko, Kamila Pulawska-Moon, Milena Doroszko, Joanna Stelmaszewska, Oliver J. Keuzer, Adolfo Rivero-Muller, Piotr Bernaczyk, Grzegorz Zalewski, Peilan Guo, Jorma Toppari, Xiangdong Li, Adam J. Ziecik, Slawomir Wolczynski, Ilpo Huhtaniemi   +15 more
doaj   +1 more source

Can Hormonal Therapy Improve the Outcomes of mTESE in Patients With Non‐Obstructive Azoospermia?

Andrology, Volume 14, Issue 6, Page 1859-1872, September 2026.
ABSTRACT Background Non‐obstructive azoospermia (NOA) represents the most severe form of male infertility. Hypogonadism is common in NOA patients, and normal testosterone (T) levels are considered essential for spermatogenesis. Fertility‐preserving hormonal therapy (FpHT) has been proposed to optimize hormonal milieu and improve sperm retrieval rates ...
Mattia Anfosso, Maria Schubert, Jann‐Frederik Cremers, Sabine Kliesch, Michael Zitzmann, Simone Bier   +5 more
wiley   +1 more source

A mAb against surface-expressed FSHR engineered to engage adaptive immunity for ovarian cancer immunotherapy

JCI Insight, 2022
Despite advances in ovarian cancer (OC) therapy, recurrent OC remains a poor-prognosis disease. Because of the close interaction between OC cells and the tumor microenvironment (TME), it is important to develop strategies that target tumor cells and ...
Devivasha Bordoloi, Pratik S. Bhojnagarwala, Alfredo Perales-Puchalt, Abhijeet J. Kulkarni, Xizhou Zhu, Kevin Liaw, Ryan P. O’Connell, Daniel H. Park, Daniel W. Kulp, Rugang Zhang, David B. Weiner   +10 more
doaj   +1 more source