Culture of bovine ovarian follicle wall sections maintained the highly estrogenic profile under basal and chemically defined conditions [PDF]
Follicle cultures reproduce in vitro the functional features observed in vivo. In a search for an ideal model, we cultured bovine antral follicle wall sections (FWS) in a serum-free defined medium (DM) known to induce 17β-estradiol (E2) production, and ...
Bocca, Anamélia Lorenzetti+7 more
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Despite advances in ovarian cancer (OC) therapy, recurrent OC remains a poor-prognosis disease. Because of the close interaction between OC cells and the tumor microenvironment (TME), it is important to develop strategies that target tumor cells and ...
Devivasha Bordoloi+10 more
doaj +1 more source
Role of androgen and gonadotrophins in the development and function of the Sertoli cells and Leydig cells: data from mutant and genetically modified mice [PDF]
Development and maintenance of the male phenotype and establishment of fertility are all dependent upon the activity of the Sertoli cells and Leydig cells of the testis.
Abel, M.H.+4 more
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Is polycystic ovary syndrome a sexual conflict? A review [PDF]
Several studies have attempted to explain the high overall prevalence of polycystic ovary syndrome among women worldwide (about 4-10%) despite its link to subfertile phenotypes. For this reason, it is considered an evolutionary paradox.
BRIGANTE, Giulia+2 more
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Immunohistochemical detection of FSH receptors in pituitary adenomas and adrenal tumors
<p><strong> </strong></p><p><strong><em>Objectives</em></strong>. Follicle stimulating hormone (FSH) receptors (FSHR) are physiologically expressed in the ovary and testis.
Marek Pawlikowski+4 more
doaj +1 more source
A Spatial Simulation Approach to Account for Protein Structure When Identifying Non-Random Somatic Mutations [PDF]
Background: Current research suggests that a small set of "driver" mutations are responsible for tumorigenesis while a larger body of "passenger" mutations occurs in the tumor but does not progress the disease.
Bjornson, Robert+6 more
core +2 more sources
Core fucosylation regulates the ovarian response via FSH receptor during follicular development
Introduction: Ovarian low response to follicle-stimulating hormone (FSH) causes infertility featuring hypergonadotropic hypogonadism, ovarian failure, and/or defective ovarian response.
Tiantong Wang+9 more
doaj +1 more source
Modulation of neurotransmission is key for organismal responses to varying physiological contexts such as during infection, injury, or other stresses, as well as in learning and memory and for sensory adaptation. Roles for cell autonomous neuromodulatory
Morgan Buckley+22 more
doaj +1 more source
Celebration Schedule 2015 (Friday)
Full presentation schedule for Celebration, Friday, May 1 ...
Provost\u27s Office,
core
Analysis of interfacial shrinkage stresses in patch repairs [PDF]
This paper presents simple analytical expressions that predict the interfacial shrinkage stresses in a repair patch over time. Four repair materials (L2, L3, L4 and G1) were applied by spraying (gunite) to unpropped compression members of two highway ...
Bennison P.+6 more
core +1 more source