Results 91 to 100 of about 29,516 (230)
Background Previous evidence regarding the associations of free triiodothyronine (FT3) and free thyroxine (FT4) with blood pressure (BP) were scarce. We aimed to explore the associations of FT3 and FT4 with BP (systolic BP [SBP], diastolic BP [DBP] and ...
Hongli Dong, Ping Hu, Jie Wang, Nan Lu
doaj +1 more source
Hyperthyroidism induces sex‐ and region‐specific glial reactivity without correlation to the noncognitive, non‐depressive behavioral changes in mice. ABSTRACT Background Glial reactivity is implicated in hyperthyroidism‐associated cognitive and psychiatric disorders, yet in vivo imaging evidence of glial reactivity in hyperthyroidism remains to be ...
Qianqian Xue +7 more
wiley +1 more source
Genetic, environmental, and phenotypic correlations between TSH and fT4 levels.
Genetic, environmental, and phenotypic correlations between TSH and fT4 levels.
Young Ki Lee (513590) +3 more
core +1 more source
This patient was admitted to the hospital 43 h after birth with convulsions and hypoglycemia, presenting as recurrent refractory hypoglycemia that was difficult to control with conventional medication. Whole exome sequencing detected the GLUD1 (NM_005271.3:c.1495G>T, p.Gly499Cys) variant, which was a de novo variant in the patient and was not detected ...
Tingyu Li +6 more
wiley +1 more source
Background Thyroid hormones deeply influence the cardiovascular system; however, the association between the fT3/fT4 ratio and the clinical outcome in euthyroid patients with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention
Tongtong Yu +7 more
doaj +1 more source
Increased Brown Adipose Tissue Thermogenesis in Phenylketonuria
In phenylketonuria (PKU), elevated phenylalanine (Phe) increases hepatic fibroblast growth factor 21 (FGF21) and thyroid hormones, enhancing brown adipose tissue (BAT) thermogenesis in patients. Central FGF21 reproduces this phenotype in rodents via reduced hypothalamic AMP‐activated protein kinase (AMPK) activity in the ventromedial nucleus of the ...
Noemí López‐Rey +18 more
wiley +1 more source
Background A low fT3/fT4 ratio has been associated with poorer prognosis in several diseases. Inflammatory indexes (IIs) and the skeletal muscle index (SMI) are established prognostic factors in various cancer types.
Valentina Tuninetti +20 more
doaj +1 more source
The Boruta‐XGBoost based risk prediction model, combined with SHAP interpretation, demonstrated high predictive accuracy and robust interpretability for forecasting hospital readmission or death during the vulnerable phase in elderly heart failure patients. This model can assist clinicians to identify high‐risk individuals, supporting clinical decision‐
Hao Luo +10 more
wiley +1 more source
Declining free thyroxine levels over time in irradiated childhood brain tumor survivors
Objective: The incidence of cranial radiotherapy (cRT)–induced central hypothyroidism (TSHD) in childhood brain tumor survivors (CBTS) is reported to be low. However, TSHD may be more frequent than currently suspected, as its diagnosis is challenging due
Laura van Iersel +14 more
doaj +1 more source
ABSTRACT Background Graves' disease presents unique challenges in pregnancy due to the risk of neonatal morbidity and mortality from maternal TSH Receptor antibodies (TRAb). A maternity hospital in Queensland has implemented a policy to identify at‐risk neonates and facilitate follow‐up, including cord blood TRAb, thyroid function tests (TFTs), and ...
Umesha Pathmanathan +2 more
wiley +1 more source

