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FTO and Obesity: Mechanisms of Association
Current Diabetes Reports, 2014The Fat mass and obesity associated (FTO) gene is a newly identified genetic factor for obesity. However, the exact molecular mechanisms responsible for the effect of FTO on obesity remain largely unknown. Recent studies from genome-wide associated studies reveal that genetic variants in the FTO gene are associated not only with human adiposity and ...
Yong-Liang Zhao, Yun-Gui Yang
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The role and mechanism of FTO in pulmonary vessels
Biotechnology and Genetic Engineering Reviews, 2023Pulmonary vascular remodeling (PVR) is the main factor of pulmonary hypertension (PH). The pathological characteristics of PVR are vascular smooth muscle hyperplasia, hypertrophy, and extensive damage. In vivo experiments, the expression of FTO in PH rat lung tissues of different rat models of hypoxia PH was observed by immunohistochemical method. mRNA
Jing, Xu +3 more
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Thickness Dependence of FTO Over-Layer on Properties of FTO/FZO Bilayer
Materials and Manufacturing Processes, 2013To realize transparent conducting oxide (TCO) films with the combined desirable characteristics of both SnO2 and ZnO, SnO2:F/ZnO:F bilayered thin films were fabricated with varying thickness of over-layer using a simplified spray pyrolysis technique. The electrical studies revealed that the bilayered films exhibit lesser sheet resistance (Rsh) than the
K. Ravichandran +6 more
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Trends in Endocrinology & Metabolism, 2011
An understanding of the mechanisms underlying body-weight regulation is crucial to tackle the growing problem of obesity. Recent technological advances in the analysis of genetic variation have given novel insights into the molecular basis of common disease.
Larder, Rachel +4 more
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An understanding of the mechanisms underlying body-weight regulation is crucial to tackle the growing problem of obesity. Recent technological advances in the analysis of genetic variation have given novel insights into the molecular basis of common disease.
Larder, Rachel +4 more
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SSRN Electronic Journal, 2011
From the jungles of the Philippines and Colombia to the deserts of Yemen and Somalia, from the mountains of Afghanistan and Pakistan to the cities of the United States and Northern Ireland, 2010 demonstrated that the threat posed by international terrorist organizations is not waning. “Death by a thousand cuts” is what al Qaida in the Arabian Peninsula
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From the jungles of the Philippines and Colombia to the deserts of Yemen and Somalia, from the mountains of Afghanistan and Pakistan to the cities of the United States and Northern Ireland, 2010 demonstrated that the threat posed by international terrorist organizations is not waning. “Death by a thousand cuts” is what al Qaida in the Arabian Peninsula
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Unraveling the Function of FTO Variants
New England Journal of Medicine, 2015Body-mass index (BMI), which represents a complex trait with high heritability, is a clinically relevant surrogate for obesity.1 Genomewide association studies have identified nearly 10,000 genetic polymorphisms in single-nucleotide variants (SNVs) associated with various human disorders and traits.
Clifford J, Rosen, Julie R, Ingelfinger
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FTO – SnSe HETEROJUNCTION FOR PHOTOVOLTAIC CONVERSION
Japanese Journal of Applied Physics, 1990FTO/SnSe heterojunctions have been fabricated onto glass substrates. It has been observed that photocurrent shows a maximum around 735 nm. Incident light intensity current characteristics show linearity upto 45 mW ·cm-2, beyond which saturation in short circuit current is obtained. An efficiency ( η) of about 2% is obtained for these cells.
J. P. Singh, R. K. Bedi
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Programming effects of
AbstractIt is becoming increasingly recognized that early‐life nutritional, metabolic and environmental factors can have a long‐term impact on the early onset of obesity, type 2 diabetes and cardiovascular diseases. Numerous experimental and epidemiological observations support the concept that an individual's response to their adult lifestyle and ...
S, Sebert +6 more
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FTO and Obesity: A Problem for a Billion People
Journal of Neuroendocrinology, 2012SummaryIt is an inescapable fact that obesity results from consuming more energy than you burn. The interesting question, however, is why some people eat more than others? Recent genetic analyses have revealed that variations in the fat mass and obesity‐associated (FTO) gene are robustly associated with obesity and increased food intake.
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2020
Introduction: Obesity is a multifactorial disease. There are currently 1, 700, 000 overweight people in the world (of which 300, 000 are obese). That is why new solutions, ways and approaches to the prevention and treatment of obesity are being sought today.
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Introduction: Obesity is a multifactorial disease. There are currently 1, 700, 000 overweight people in the world (of which 300, 000 are obese). That is why new solutions, ways and approaches to the prevention and treatment of obesity are being sought today.
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