Results 51 to 60 of about 1,840 (163)

Ampicillin-Resistant β-lactamase-negative Haemophilus Influenzae Strains Isolated in the Czech Republic in 2010-2018 [PDF]

open access: yes, 2022
Ampicillin-resistant β-lactamase- negative Haemophilus influenzae strains isolated in the Czech Republic in 2010-2018 According to the results of regular surveillance of resistance of bacterial pathogens of respiratory tract infections, the number of ...
Jakubů, Vladislav
core  

Revisiting cefditoren for the treatment of community-acquired infections caused by human-adapted respiratory pathogens in adults

open access: yesMultidisciplinary Respiratory Medicine, 2018
Fifteen years after its licensure, this revision assesses the role of cefditoren facing the current pharmacoepidemiology of resistances in respiratory human-adapted pathogens (Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae and ...
María-José Giménez   +2 more
doaj   +1 more source

Detection of Protein–Protein Interactions in Escherichia coli With Single Molecule Sensitivity

open access: yesAdvanced Science, Volume 13, Issue 37, 3 July 2026.
This article describes a regulatory circuit in Escherichia coli able to detect protein–protein interactions with exquisite sensitivity. The interaction between two hybrid proteins fused to Bordetella pertussis adenylate cyclase and its activator calmodulin triggers a potent cyclic AMP signaling cascade.
Marilyne Davi, Daniel Ladant
wiley   +1 more source

In vivo cell division gene product interactions in Escherichia coli K-12 [PDF]

open access: yes, 1987
Overexpression of plasmid-coded PBP 3 was analyzed in strains harboring ftsA, ftsH, pbpB (ftsI), ftsQ, ftsZ, or recA441 (Tif) mutations. Higher cellular levels of PBP 3, the pbpB gene product, could not restore septum formation of ftsA, ftsQ, ftsZ, and ...
Betzner, A.   +3 more
core   +1 more source

Direct interaction between MreB and the RodA‐PBP2 complex organizes lateral cell wall synthesis in Escherichia coli

open access: yesmLife, Volume 5, Issue 3, Page 325-338, June 2026.
Abstract The elongasome, or the Rod complex, orchestrates lateral peptidoglycan (PG) synthesis in many rod‐shaped bacteria. It consists of the actin‐like protein MreB, the PG synthase RodA‐PBP2 complex, as well as MreCD and RodZ. Although the loss or disruption of any elongasome component results in a loss of rod shape, previous studies found that a ...
Rui Zhan   +5 more
wiley   +1 more source

A novel PBP3 substitution in Haemophilus influenzae confers reduced aminopenicillin susceptibility

open access: yesBMC Microbiology, 2018
Background Identification and characterization of non-typeable Haemophilus influenzae (NTHi) with reduced susceptibility to β-lactam antibiotics due to mutations in penicillin binding protein 3 (PBP3) is a clinical challenge. We analyzed a blood isolate,
John Thegerström   +4 more
doaj   +1 more source

Incidence of Cefotaxime‐Resistant Haemophilus influenzae Is Linked to Regional Consumption of Oral Aminopenicillins and Parenteral Third‐Generation Cephalosporins in Norway

open access: yesAPMIS, Volume 134, Issue 4, April 2026.
ABSTRACT The emergence of cefotaxime‐resistant Haemophilus influenzae (CRHI) in Norway during the 2000s coincided with increased use of oral aminopenicillins and parenteral third‐generation cephalosporins. This study examined associations between beta‐lactam consumption and CRHI incidence. Surveillance data on antibiotic usage across Norwegian regions (
Dagfinn Skaare, Gunnar Skov Simonsen
wiley   +1 more source

Cefuroxime resistance in non-β-lactamase Haemophilus influenzae is linked to mutations in ftsI [PDF]

open access: yes, 2003
The penicillin binding protein (PBP) genes dacA, dacB and ftsI from 14 cefuroxime-resistant (CXM(R)) isolates and three clinical isolates with low CXM MIC for non-beta-lactamase-producing Haemophilus influenzae type b were molecularly characterized.
Straker, K   +5 more
core  

SanA Plays a Role in Peptidoglycan Integrity in Escherichia coli

open access: yesMolecular Microbiology, Volume 125, Issue 4, Page 343-357, April 2026.
SanA is a novel regulator of peptidoglycan synthesis, potentially through functional interplay with PBP1B‐dependent pathways. ABSTRACT Peptidoglycan synthesis and degradation are both essential for bacterial growth, and damaged peptidoglycan must be continuously repaired. In Escherichia coli, peptidoglycan required for cell elongation is synthesized by
Honoka Yamaguchi   +6 more
wiley   +1 more source

Contribution of ROB-1 and PBP3 mutations to the resistance phenotype of a β-lactamase-positive amoxicillin/clavulanic acid-resistant Haemophilus influenzae carrying plasmid pB1000 in Italy. [PDF]

open access: yes, 2011
OBJECTIVES: plasmid pB1000 bearing bla(ROB-1) is responsible for high-level β-lactam resistance in Haemophilus influenzae as well as in Pasteurella multocida and Haemophilus parasuis isolates from Spain.
San Millan, A   +7 more
core   +1 more source

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