Results 61 to 70 of about 1,840 (163)

Chorioamnionitis in the Second Trimester Secondary to Multidrug‐Resistant Haemophilus influenzae Infection

Case Reports in Infectious Diseases, Volume 2026, Issue 1, 2026.
Purpose Nontypeable Haemophilus influenzae (NTHi) is an emerging perinatal pathogen linked to chorioamnionitis, preterm birth, and early pregnancy loss. This case report describes the presentation, microbiologic findings, and management of second‐trimester NTHi‐associated chorioamnionitis, emphasizing diagnostic challenges and antimicrobial ...
Karen S. Carlson, Morgan Baker Korthals, Priya Gusain   +2 more
wiley   +1 more source

Quorum-sensing regulator sdiA and marA overexpression is involved in in vitro-selected multidrug resistance of Escherichia coli [PDF]

, 2010
The role of sdiA in the acquisition of low-level multidrug resistance (MDR) was analysed and compared with that of marA and soxS in two Escherichia coli clinical isolates and two in vitro-selected mutants.The mutants were developed by growth in ...
Antunes, Nuno T., Sánchez-Céspedes, Javier, Aquili, Virginia D., Poveda, José B., Vila, Jordi, Tavío, María M.   +5 more
core   +1 more source

A Review of β‐Lactamase Inhibitors in Clinical Use and Development: Mechanisms, Spectrum, and Therapeutic Applications

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
β‐Lactam antibiotics have long served as a cornerstone for treating bacterial infections. However, their widespread and often indiscriminate use has fueled the emergence of multidrug‐resistant Gram‐negative pathogens, primarily through the production and dissemination of β‐lactamase enzymes.
Mohammad Javad Roustaye Gourabi, Anita Nikoo, Bita Khanbabaei, Masoud Kargar, Amirhossein Fayyazi, Seyyed Mohammad Javad Mousavi, Amirhossein Aghdaee, Ali Hashemi, Javad Yasbolaghi Sharahi, Swaran J. S. Flora   +9 more
wiley   +1 more source

A four-amino-acid YRIN insertion in ftsI reduced ceftiofur susceptibility in a canine Escherichia coli isolate

One Health Advances
Ceftiofur resistance in canine clinical Escherichia coli is usually associated with extended-spectrum β-lactamases (ESBLs) or AmpC β-lactamases. However, some isolates display elevated ceftiofur minimum inhibitory concentrations (MICs) without carrying ...
Xukun Dang, Zeshi Chen, Rina Bai, Junyao Jiang, Weishuai Zhai, Shizhen Ma, Lu Liu, Dejun Liu, Zhaofei Xia, Zhangqi Shen, Yang Wang, Siyu Chen   +11 more
doaj   +1 more source

Trimetallic Nanozyme‐Embedded Smart Hydrogel Enables NIR‐Controlled Bacterial Killing and Oxidative Stress Alleviation

Advanced Science, Volume 12, Issue 48, December 29, 2025.
A microenvironment‐responsive hydrogel is developed incorporating polymyxin B‐modified AuMnCu nanozymes and dual drugs (tannic acid and tobramycin). At infection sites, it generates ROS, releases drugs responsively, and enhances mild photothermal action to disrupt bacterial redox balance.
Zehui Xiao, Jiangli Cao, Jifeng Liu, Zhiyong Song, Ting Du, Xinjun Du   +5 more
wiley   +1 more source

Carbapenem-Nonsusceptible Haemophilus influenzae with Penicillin-Binding Protein 3 Containing an Amino Acid Insertion [PDF]

, 2018
The prevalence of β-lactamase-negative ampicillin-resistant (BLNAR) Haemophilus influenzae has become a clinical concern. In BLNAR isolates, amino acid substitutions in penicillin-binding protein 3 (PBP3) are relevant to the β ...
Jin, Wanchun, Kazuki Kitaoka, Kitaoka, Kazuki, Arakawa, Yoshichika, Wanchun Jin, Jun-ichi Wachino, Hiromitsu Kitanaka, Kitanaka, Hiromitsu, Kouji Kimura, Hirotsugu Banno, Kimura, Kouji, Wachino, Jun-ichi, Yoshichika Arakawa, Banno, Hirotsugu   +13 more
core   +1 more source

ZapA uses a two‐pronged mechanism to facilitate Z ring formation in Escherichia coli

mLife, Volume 4, Issue 6, Page 602-622, December 2025.
Abstract The tubulin‐like protein FtsZ assembles into the Z ring that leads to the assembly and activation of the division machinery in most bacteria. ZapA, a widely conserved protein that interacts with FtsZ, plays a pivotal role in organizing FtsZ filaments into a coherent Z ring.
Yuanyuan Cui, Han Gong, Di Yan, Hao Li, Wenjie Yang, Ying Li, Xiangdong Chen, Joe Lutkenhaus, Sheng‐You Huang, Xinxing Yang, Shishen Du   +10 more
wiley   +1 more source

Characterization of CrgA, a New Partner of the Mycobacterium tuberculosis Peptidoglycan Polymerization Complexes [PDF]

, 2011
The role(s) in cell division of the Mycobacterium tuberculosis Rv0011c gene product, a homolog of the Streptomyces CrgA protein that is responsible for coordinating growth and cytokinesis in sporogenic ...
P. Plocinski, M. Ziolkiewicz, M. Madiraju, S. I. Vadrevu, M. Kiran, T. A. Cross, J. Dziadek, C. Veckerle, H. B. Nguyen, M. Arthur, J. Hugonnet, M. Rajagopalan   +11 more
core   +1 more source

MOESM3 of Stepwise evolution and convergent recombination underlie the global dissemination of carbapenemase-producing Escherichia coli [PDF]

, 2020
Additional file 3: Table S3. Oligonucleotides used in this work. Table S4. Mutations detected in MG1655 strains derivatives mutated in ftsI. Table S5. Genomic features of the E. coli ST410 isolate Ec-MAD. Table S6.
Monzer Hamze (679195), Remy Bonnin (8331708), Philippe Glaser (380391), Rafael Patiño-Navarrete (8331711), Lauraine Gauthier (3716500), Nicolas Cabanel (3636589), Julie Takissian (3114201), Jean-Yves Madec (120907), Thierry Naas (112513), Isabelle Rosinski-Chupin (246239)   +9 more
core   +1 more source

Mutations in porin LamB contribute to ceftazidime-avibactam resistance in KPC-producing Klebsiella pneumoniae [PDF]

, 2021
Ceftazidime-avibactam (CAZ-AVI) shows promising activity against carbapenem-resistant Klebsiella pneumoniae (CRKP), however, CAZ-AVI resistance have emerged recently. Mutations in KPCs, porins OmpK35 and/or OmpK36, and PBPs are known to contribute to the
Zhiwei Lin (1423945), Yitan Li (1449217), Baomo Liu (3619250), Jiong Wang (440497), Feifeng Li (11471198), Ying Jiang (5910), Chuyue Zhuo (11471195), Chao Zhuo (277585), Ningjing Liu (11471192), Shunian Xiao (11471204), Yingyi Guo (11471189), Xiaoliang Ba (161131), Likang Yao (11471201)   +12 more
core   +1 more source