Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method [PDF]
Ampicillin resistance in Haemophilus influenzae due to alterations in penicillin-binding proteins (beta-lactamase negative ampicillin resistant [BLNAR]) is acquiring increasing clinical and epidemiological importance.
Pérez-Vázquez, María +6 more
core +1 more source
Aztreonam–avibactam: The dynamic duo against multidrug‐resistant gram‐negative pathogens
Abstract Antimicrobial resistance poses a significant public health challenge, particularly with the rise of gram‐negative hospital‐acquired infections resistant to carbapenems. Aztreonam–avibactam (ATM–AVI) is a promising new combination therapy designed to combat multidrug‐resistant (MDR) gram‐negative bacteria, including those producing metallo‐β ...
Mohammed Al Musawa +5 more
wiley +1 more source
Escherichia coli multi-locus sequence type ST131 is a globally distributed pandemic lineage that causes multidrug-resistant extra-intestinal infections. ST131 E.
Shu-Ting Cho +7 more
doaj +1 more source
Salmonella encodes two peptidoglycan synthases, PBP3 and PBP3SAL, which can promote cell division independently. This study shows by in vivo cross‐linking and proteomics that PBP3 and PBP3SAL do not interact in the division complex and that ~40 proteins may associate direct or indirectly to these enzymes, including expected divisome components and new ...
Sónia Castanheira +3 more
wiley +1 more source
ZipA Is Required for Recruitment of FtsK, FtsQ, FtsL, and FtsN to the Septal Ring in Escherichia coli [PDF]
The septal ring in Escherichia coli consists of at least nine essential gene products whose order of assembly resembles a mostly linear dependency pathway: FtsA and ZipA directly bind FtsZ polymers at the prospective division site,
Cynthia A. Hale, Piet A. J. de Boer
core +1 more source
Molecular epidemiology of nontypeable haemophilus influenzae causing community-acquired pneumonia in adults [PDF]
Nontypeable Haemophilus influenzae (NTHi) is an opportunistic pathogen which causes a variety of respiratory infections. The objectives of the study were to determine its antimicrobial susceptibility, to characterize the b-lactam resistance, and to ...
Puig Pitarch, Carmen +7 more
core +4 more sources
The peptidoglycan (PG) hydrolase PBP7 localizes to both the lateral cell envelope and midcell in Escherichia coli, and its midcell localization is dependent on an active divisome. PBP7 influences the timing of FtsZ and FtsN assembly within the divisome. In the absence of PBP7, FtsN assembly is slower and septal PG synthesis is reduced in the absence of
Xinwei Liu +4 more
wiley +1 more source
Haemophilus influenzae carriage and antibiotic resistance profile in Belgian infants over a three-year period (2016\u20132018) [PDF]
: Background: Non-typeable Haemophilus influenzae has become increasingly important as a causative agent of invasive diseases following vaccination against H. influenzae type b.
Willen, Laura +13 more
core
Jiansheng Lin,1,2 Yinna Wang,2 Chunli Lin,2 Ran Li,3 Gaoxiong Wang1,4 1School of Public Health of Fujian Medical University, Fuzhou, People’s Republic of China; 2Microbiology Laboratory, Quanzhou Women’s and Children’s Hospital, Quanzhou, People’s ...
Lin J, Wang Y, Lin C, Li R, Wang G
doaj
Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain:recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime [PDF]
The sequence of the ftsI gene encoding the transpeptidase domain of penicillin-binding protein 3 (PBP 3) was determined for 354 nonconsecutive Haemophilus influenzae isolates from Spain; 17.8% of them were ampicillin susceptible, 56% were beta-lactamase ...
Pérez-Vázquez, María +8 more
core +1 more source

