Results 181 to 190 of about 6,427 (219)

Endothelial viral inclusions in Fuchs' corneal dystrophy

Human Pathology, 1987
A case of Fuchs' corneal dystrophy is presented. The patient, a 70-year-old white woman, had bilateral decreasing vision, especially while reading and driving at night. Clinical features were characteristic of Fuchs' corneal dystrophy. Ultrastructural studies demonstrated findings in Descemet's membrane typical of those previously reported with ...
S I, Roth, E L, Stock, R, Jutabha
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Regenerative Therapy for Fuchs Endothelial Corneal Dystrophy

Cornea, 2018
Purpose: Fuchs endothelial corneal dystrophy (FECD) is an acquired corneal endotheliopathy and is one of the most common indications for corneal transplantation surgery worldwide. Endothelial keratoplasty (EK) is the most popular form of corneal transplantation for FECD. In standard EK surgery, the patient's corneal endothelium
Yu Qiang, Soh, Jodhbir S, Mehta
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Cancer Risk in Patients With Fuchs Endothelial Corneal Dystrophy

Cornea, 2021
Purpose: The purpose of this study is to quantify cancer risk in patients with Fuchs endothelial corneal dystrophy (FECD). Methods: Using the 2014 to 2016 Medicare Limited 5% Data Sets—Carrier Line File, US Medicare fee-for-service beneficiaries (aged 65 years or older) with FECD ...
Timothy T. Xu, Keith H. Baratz, Michael P. Fautsch, David O. Hodge, Michael A. Mahr   +4 more
openaire   +2 more sources

Fuchs Endothelial Corneal Dystrophy and Mitochondria

Cornea, 2018
Abstract: Fuchs endothelial corneal dystrophy (FECD) is a bilateral progressive corneal endothelial disease characterized by guttae, which present as partial Descemet membrane thickening, inducing corneal edema at the final stage. Oxidative stress has been reported to play an important role in the pathogenesis of FECD.
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The Molecular Basis of Fuchs’ Endothelial Corneal Dystrophy

Molecular Diagnosis & Therapy, 2019
Fuchs' endothelial corneal dystrophy (FECD) is a common disease resulting from corneal endothelial cell dysfunction. It is inherited in an autosomal dominant fashion with incomplete penetrance, and with a female bias. Approximately half of cases occur sporadically, and the remainder are familial. Early and late-onset forms of the disease exist.
Jie Zhang, Charles N. J. McGhee, Dipika V. Patel   +2 more
openaire   +3 more sources

Diurnal Variation in Corneal Edema in Fuchs Endothelial Corneal Dystrophy

American Journal of Ophthalmology, 2019
The extent of diurnal variation in corneal edema in Fuchs dystrophy is unknown. We measured corneal thickness and posterior profile over the course of the day using Scheimpflug imaging.Prospective cohort study.Participants with clinically advanced Fuchs dystrophy eyes undergoing endothelial keratoplasty and participants with healthy corneas were ...
Marianne Fritz, Viviane Grewing, Philip Maier, Thabo Lapp, Daniel Böhringer, Thomas Reinhard, Katrin Wacker   +6 more
openaire   +3 more sources

Genotyping methods for Fuchs corneal endothelial dystrophy

Journal Français d'Ophtalmologie
Fuchs endothelial corneal dystrophy (FECD) is a genetic degenerative disease characterized by the progressive degradation of the corneal endothelium, often leading to vision loss. It is the leading cause of corneal transplantation in the Western world. FECD is more common in Europe and the United States, particularly among women.
D. Onitiu, I. Harzallah, H. Vaitinadapoule, F. Mascarelli, R. Touraine, Z. He, O. Dorado-Cortez, M.C. Trone, P. Gain, G. Thuret   +9 more
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Molecular genetic aspects of Fuchs’ endothelial corneal dystrophy pathogenesis

Vestnik oftal'mologii, 2020
Fuchs' corneal dystrophy (FCD) is a common bilateral non-inflammatory endothelial pathology. It is a multigenic disorder with various expressivity, penetrance and population prevalence. This review discusses corneal endothelium pump function, FCD pathogenesis and its known genetic factors.
S V, Trufanov, N V, Fisenko
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Fuchs endothelial corneal dystrophy: an updated review

International Ophthalmology
The present review will summarize FECD-associated genes and pathophysiology, diagnosis, current  therapeutic approaches, and future treatment perspectives.Literature review.Fuchs' endothelial corneal dystrophy (FECD) is the most common bilateral corneal dystrophy and accounts for one-third of all corneal transplants performed in the US.
Francisco Altamirano, Gustavo Ortiz-Morales, Mario A. O’Connor-Cordova, Juan Pablo Sancén-Herrera, Judith Zavala, Jorge E. Valdez-Garcia   +5 more
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Factors Influencing Visual Acuity in Fuchs’ Endothelial Corneal Dystrophy

Optometry and Vision Science, 2018
ABSTRACT SIGNIFICANCE In eyes with mild Fuchs’ endothelial corneal dystrophy without significant corneal edema, objective scattering index has the strongest influence on distance visual acuity, followed by the anterior corneal densitometry.
Hidenaga, Kobashi, Kazutaka, Kamiya, Kimiya, Shimizu   +2 more
openaire   +2 more sources