Results 11 to 20 of about 3,843 (175)

Regenerative medicine in Fuchs' endothelial corneal dystrophy

Taiwan Journal of Ophthalmology, 2021
The management of Fuchs' endothelial corneal dystrophy (FECD) has evolved rapidly since the introduction of endothelial keratoplasty (EK). In recent years, advances in our understanding of endothelial cell biology, in particular with respect to the ...
Amy E Yuan, Roberto Pineda
doaj   +3 more sources

Fuchs endothelial corneal dystrophy: current perspectives

Clinical Ophthalmology, 2016
Gustavo Vedana, Guadalupe Villarreal Jr, Albert S Jun Wilmer Eye Institute, Johns Hopkins Medical Institutions, Baltimore, MD, USA Abstract: Fuchs endothelial corneal dystrophy (FECD) is the most common corneal dystrophy and frequently results in ...
Vedana G, Villarreal Jr G, Jun AS
doaj   +5 more sources

Update on the Surgical Management of Fuchs Endothelial Corneal Dystrophy [PDF]

Ophthalmology and Therapy, 2020
Fuchs endothelial corneal dystrophy (FECD) is the most common posterior corneal dystrophy and the leading indication for corneal transplantation in the United States.
Andrea L. Blitzer, Kathryn A. Colby
doaj   +3 more sources

Cataract surgery in patients with Fuchs’ endothelial corneal dystrophy

Community Eye Health Journal, 2019
Cataract surgery risks corneal decompensation in patients with Fuchs’ endothelial corneal dystrophy, but it can also be combined with endothelial keratoplasty to address the condition.
Soujanya Kaup, Suresh K Pandey
doaj   +2 more sources

Fuchs' Endothelial Corneal Dystrophy and Cardiometabolic Comorbidities. [PDF]

Ophthalmology
In this retrospective study utilizing data from the National Institutes of Health All of Us Research Program, individuals with Fuchs' endothelial corneal dystrophy (n=548) exhibited a higher burden of cardiometabolic disease than matched controls (n=5,480).
Mihalache A, Huang RS, Popovic MM, Chan CC.   +3 more
europepmc   +3 more sources

Exploring the histopathological signature of repeat-mediated Fuchs endothelial corneal dystrophy. [PDF]

Acta Ophthalmol
Abstract Purpose To determine the histological differences between Fuchs endothelial corneal dystrophy (FECD) cases with and without the most common genetic risk factor, expansion of a CTG repeat (CTG18.1) within the TCF4 gene. Methods Formalin‐fixed paraffin‐embedded corneal tissues were compared retrospectively, and CTG18.1 status was determined from
Kladny AS, Bhattacharyya N, Abreu Costa M, Tuft SJ, Thaung C, Davidson AE.   +5 more
europepmc   +2 more sources

Fuchs Endothelial Corneal Dystrophy [PDF]

JAMA Ophthalmology, 2014
First described more than a century ago, Fuchs endothelial corneal dystrophy (FECD) is a common disease characterized by progressive loss of endothelial cells, thickening of the Descemet membrane, and deposition of extracellular matrix in the form of guttae.
Angela Y, Zhu, Charles G, Eberhart, Albert S, Jun   +2 more
openaire   +2 more sources

Pathological classification of Fuchs endothelial corneal dystrophy into several types and their relationships with CTG18.1 expansion repeats. [PDF]

J Pathol
Abstract Late‐onset Fuchs endothelial corneal dystrophy (FECD) is the most common primary disease of the corneal endothelium and the leading indication for corneal transplantation in Western countries. It is characterized by progressive accumulation, over two to three decades, of extracellular matrix (ECM) components in Descemet's membrane (DM ...
Vaitinadapoulé H, Onitiu D, Maurin C, Travers G, Crouzet E, Dorado-Cortez O, Poinard S, He Z, Forest F, Ollier E, Touraine R, Gain P, Perone JM, Thuret G, French Fuchs Study Group (FFSG).   +14 more
europepmc   +2 more sources

Fuchs' Endothelial Corneal Dystrophy [PDF]

Ophthalmology, 2013
To assess interobserver agreement between 2 corneal specialists grading Fuchs' dystrophy clinically and to determine if the corneal central-to-peripheral thickness ratio (CPTR) may be an alternative and objective metric of disease severity.Cross-sectional study.Forty-five eyes (26 subjects) with mild and moderate Fuchs' dystrophy, 73 eyes (60 subjects)
Daniel J, Repp, David O, Hodge, Keith H, Baratz, Jay W, McLaren, Sanjay V, Patel   +4 more
openaire   +2 more sources

Imaging the Corneal Endothelium in Fuchs Corneal Endothelial Dystrophy [PDF]

Seminars in Ophthalmology, 2019
Fuchs endothelial corneal dystrophy (FECD) is characterized by the progressive degeneration of the corneal endothelium (CE). The purpose of this article is to review the diagnostic tools available to image and assess the CE in FECD. Slit-lamp biomicroscopy with specular reflection and retroillumination are important techniques to assess the CE ...
Stephan Ong Tone, Ula Jurkunas
openaire   +2 more sources