Results 31 to 40 of about 6,427 (219)

Fuchs endothelial corneal dystrophy and corneal endothelial diseases: East meets West [PDF]

open access: yesEye, 2019
Fuchs endothelial corneal dystrophy (FECD) is amongst one of the most common indications for endothelial keratoplasty worldwide. Despite being originally described among Caucasians, it is now known to be prevalent among a large number of populations, including Asians.
Y Q, Soh   +3 more
openaire   +2 more sources

Outcome of Two Corneal Collagen Crosslinking Methods in Bullous Keratopathy due to Fuchs’ Endothelial Dystrophy

open access: yesCase Reports in Medicine, 2014
Four eyes of 2 patients with corneal edema due to Fuchs’ endothelial dystrophy were treated with CXL using the standard protocol. Since no improvement in visual acuity, corneal clarity, thickness, or pain sensation was evident in any eye at month 12, 2 ...
Omur O. Ucakhan, Ayhan Saglik
doaj   +1 more source

Cataract surgery in patients with Fuchs’ dystrophy and corneal decompensation indicated for Descemet's membrane endothelial keratoplasty

open access: yesScientific Reports, 2022
The availability of corneal donor tissue is limited in most developing countries. This study evaluated whether patients with coexisting cataract and Fuchs’ dystrophy with corneal decompensation awaiting Descemet’s membrane endothelial keratoplasty (DMEK)
Wei-Yi Chou, Yih-Shiuan Kuo, Pei-Yu Lin
doaj   +1 more source

Expression and Function of ZEB1 in the Cornea

open access: yesCells, 2021
ZEB1 is an important transcription factor for epithelial to mesenchymal transition (EMT) and in the regulation of cell differentiation and transformation.
Yingnan Zhang   +5 more
doaj   +1 more source

Primary graft failure associated with epithelial downgrowth: a case report [PDF]

open access: yes, 2005
Background Epithelial downgrowth is a rare complication of ocular surgery. While the features of epithelial downgrowth following corneal transplantation are well described, its association with primary graft failure has only been reported once previously.
Anthony J Aldave   +27 more
core   +3 more sources

Dataset on transcriptome profiling of corneal endothelium from patients with Fuchs endothelial corneal dystrophy

open access: yesData in Brief, 2019
Fuchs endothelial corneal dystrophy (FECD) is a bilateral inherited eye disease with advanced forms only treatable by corneal transplantation. The pathogenesis of FECD has not been worked out yet, however, trinucleotide repeat polymorphism CTG18.1 in the
Anastasia S. Nikitina   +8 more
doaj   +1 more source

Role of the TCF4 gene intronic variant in normal variation of corneal endothelium [PDF]

open access: yes, 2012
PURPOSE: To identify early features of Fuchs endothelial dystrophy (FED) in carriers of the rs613872(G) transcription factor 4 gene (TCF4) aged 20 to 21 years.
Crawford, Geoffrey J.   +8 more
core   +1 more source

A large multi-ethnic genome-wide association study identifies novel genetic loci for intraocular pressure. [PDF]

open access: yes, 2017
Elevated intraocular pressure (IOP) is a major risk factor for glaucoma, a leading cause of blindness. IOP heritability has been estimated to up to 67%, and to date only 11 IOP loci have been reported, accounting for 1.5% of IOP variability.
Banda, Yambazi   +10 more
core   +3 more sources

Multimodal Highlighting of Structural Abnormalities in Diabetic Rat and Human Corneas. [PDF]

open access: yes, 2013
PURPOSE: This study aimed to highlight structural corneal changes in a model of type 2 diabetes, using in vivo corneal confocal microscopy (CCM). The abnormalities were also characterized by transmission electron microscopy (TEM) and second harmonic ...
Behar-Cohen, F.   +7 more
core   +5 more sources

Corneal clearance and central endothelial cell repopulation despite graft detachment after Descemet membrane endothelial keratoplasty

open access: yesGMS Ophthalmology Cases, 2019
Objective: Descemet membrane endothelial keratoplasty (DMEK) is the gold standard procedure for treatment of primary corneal endothelial disorders. Graft detachment is a frequent complication of DMEK, which often requires re-operation or re-bubbling ...
Daravagka, Maria   +3 more
doaj   +1 more source

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