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Anticancer Effects of Fucoidan

2014
Recently, there has been an increased interest in the pharmacologically active natural compounds isolated and used for remedies of various kinds of diseases, including cancer. The great deal of interest has been developed to isolate bioactive compounds from marine resources because of their numerous health beneficial effects.
Kalimuthu, Senthilkumar, Se-Kwon, Kim
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Gene identification and characterization of fucoidan deacetylase for potential application to fucoidan degradation and diversification

Journal of Bioscience and Bioengineering, 2017
Fucoidan is an α-l-fucopyranosyl polymer found in seaweeds with forms that have acetyl and sulfuric modifications and derivatives that are lower and/or diversified, with modifications that have attracted interest as potential bioactive substances. We identified the gene for a fucoidan deacetylase that cleaves acetyl moieties from fucoidan and thereby ...
Tatsuhiko Nagao   +5 more
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Progress in the study of fucoidan degradation

Carbohydrate Research
Fucoidan, a sulfated polysaccharide, demonstrates many biological activities. It has found extensive applications across medicine, food, cosmetics, and other industries. Recent investigations have highlighted that low molecular weight fucoidan (LMWF) possesses enhanced bioavailability and greater biological efficacy than its high molecular weight ...
Haifei Lv   +10 more
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Fucoidan aus Braunalgen

Deutsche Zeitschrift für Onkologie, 2021
ZusammenfassungFucoidan ist ein Polysaccharid, das in Meeresbraunalgen, vor allem der Wakame-Alge, vorkommt. Es ist in vielen Ländern Asiens Bestandteil der täglichen Ernährung mit Algen, darüber hinaus wird es in der traditionellen asiatischen Medizin zur komplementären Behandlung von Tumorerkrankungen eingesetzt.
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Advances in fucoidan and fucoidan oligosaccharides: Current status, future prospects, and biological applications

Carbohydrate Polymers
Sulfated polysaccharides (SPS) derived from seaweeds are precious bioactive compounds of diverse biological activities. Fucoidan is a complex SPS composed of L-fucose and sulfate groups, can be extracted from brown seaweeds, as well as microbial, insect, plant glycans, and marine invertebrates.
Hamed I, Hamouda   +4 more
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Fucoidan Prevents the Progression of Osteoarthritis in Rats

Journal of Medicinal Food, 2015
This study investigated the effects of fucoidan (extract from Hizikia fusiforme ) on symptoms and inflammatory cytokine activation in rats with monosodium iodoacetate (MIA)-induced osteoarthritis (OA). Forty male SD rats were divided into five groups, including normal, negative control (MIA),
Don-Gil, Lee   +8 more
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Fucoidan

2022
Ellya Sinurat   +3 more
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Computational insights into fucoidan–receptor binding: Implications for fucoidan-based targeted drug delivery

Drug Discovery Today
Fucoidan, a polysaccharide from seaweed, holds promise as a drug delivery system and immune modulator; however, its exact mechanism of action remains unclear. As various carbohydrates play key roles in immune responses by binding to carbohydrate-binding proteins like lectins, fucoidan is hypothesized to interact with immune receptors, potentially ...
Rumana, Ferdushi   +5 more
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Fucoidan in future applications – an industrial perspective

2020
Fucoidan is a sulphated biopolymer present in brown seaweeds and some other marine organisms. Current commercial fucoidan grades are derived from brown seaweeds, and their structure is dependent on seaweed source. The importance of structure will depend on type of application. With applications potentially[for full text, please go to the a.m. URL]
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[The anticoagulant activity of fucoidans].

Eksperimental'naia i klinicheskaia farmakologiia, 1997
The influence of the degree of fucoidan macromolecules sulfation on their ability to induce an anticoagulant effect was studied. In in vitro experiments with the basic stain and in in vivo experiments on rabbits with performance of Quick's test, APTT, and spectrophotometric determination of antithrombin III (AT-III) activity a direct dependence of the ...
E A, Gavrilova   +4 more
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