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Fucoidan: Structure and Bioactivity [PDF]

Molecules, 2008
Fucoidan refers to a type of polysaccharide which contains substantial percentages of L-fucose and sulfate ester groups, mainly derived from brown seaweed. For the past decade fucoidan has been extensively studied due to its numerous interesting biological activities. Recently the search for new drugs has raised interest in fucoidans.
Ruixiang Zhao
exaly   +4 more sources

Therapies from Fucoidan: New Developments [PDF]

Marine Drugs, 2019
Since our last review in 2015, the study and use of fucoidan has extended in several research areas. Clinical use of fucoidan for the treatment of renal disease has become available and human safety studies have been undertaken on radiolabeled fucoidan for the purpose of imaging thrombi.
J Helen Fitton, Damien N Stringer, Ah Young Park   +2 more
exaly   +4 more sources

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Anticancer Effects of Fucoidan

2014
Recently, there has been an increased interest in the pharmacologically active natural compounds isolated and used for remedies of various kinds of diseases, including cancer. The great deal of interest has been developed to isolate bioactive compounds from marine resources because of their numerous health beneficial effects.
Kalimuthu, Senthilkumar, Se-Kwon, Kim
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Gene identification and characterization of fucoidan deacetylase for potential application to fucoidan degradation and diversification

Journal of Bioscience and Bioengineering, 2017
Fucoidan is an α-l-fucopyranosyl polymer found in seaweeds with forms that have acetyl and sulfuric modifications and derivatives that are lower and/or diversified, with modifications that have attracted interest as potential bioactive substances. We identified the gene for a fucoidan deacetylase that cleaves acetyl moieties from fucoidan and thereby ...
Tatsuhiko Nagao, Ayako Kumabe, Fumika Komatsu, Hisashi Yagi, Hirokazu Suzuki, Takashi Ohshiro   +5 more
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Fucoidan aus Braunalgen

Deutsche Zeitschrift für Onkologie, 2021
ZusammenfassungFucoidan ist ein Polysaccharid, das in Meeresbraunalgen, vor allem der Wakame-Alge, vorkommt. Es ist in vielen Ländern Asiens Bestandteil der täglichen Ernährung mit Algen, darüber hinaus wird es in der traditionellen asiatischen Medizin zur komplementären Behandlung von Tumorerkrankungen eingesetzt.
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Progress in the study of fucoidan degradation

Carbohydrate Research
Fucoidan, a sulfated polysaccharide, demonstrates many biological activities. It has found extensive applications across medicine, food, cosmetics, and other industries. Recent investigations have highlighted that low molecular weight fucoidan (LMWF) possesses enhanced bioavailability and greater biological efficacy than its high molecular weight ...
Haifei Lv, Meicai Su, Xiaobin Hao, Kaitao Li, Xiao Zhang, Yan Wang, Xiao Tian, Zhengchao Wang, Zhangwei Qiao, Xia Li, Shuliang Song   +10 more
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Advances in fucoidan and fucoidan oligosaccharides: Current status, future prospects, and biological applications

Carbohydrate Polymers
Sulfated polysaccharides (SPS) derived from seaweeds are precious bioactive compounds of diverse biological activities. Fucoidan is a complex SPS composed of L-fucose and sulfate groups, can be extracted from brown seaweeds, as well as microbial, insect, plant glycans, and marine invertebrates.
Hamed I, Hamouda, Tang, Li, Samah, Shabana, Amr H, Hashem, Heng, Yin   +4 more
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Fucoidan Prevents the Progression of Osteoarthritis in Rats

Journal of Medicinal Food, 2015
This study investigated the effects of fucoidan (extract from Hizikia fusiforme ) on symptoms and inflammatory cytokine activation in rats with monosodium iodoacetate (MIA)-induced osteoarthritis (OA). Forty male SD rats were divided into five groups, including normal, negative control (MIA),
Don-Gil, Lee, Sang-Yong, Park, Won-Seok, Chung, Jae-Hee, Park, Eunson, Hwang, Gafurjon Tom, Mavlonov, In-Ho, Kim, Ki-Young, Kim, Tae-Hoo, Yi   +8 more
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Fucoidan: Biological Activity in Liver Diseases

The American Journal of Chinese Medicine, 2020
Fucoidan is a type of polysaccharide rich in sulfuric acid groups and is mainly found in brown algae. Due to its extensive biological activities, such as anticoagulant, antitumor, antithrombotic, antiviral, anti-oxidant and enhancing immune function, fucoidan has gradually become a research hotspot.
Jingjing, Li, Chuanyong, Guo, Jianye, Wu
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A fucoidan fraction from Ascophyllum nodosum

Carbohydrate Research, 2001
A fucoidan fraction was purified from the brown alga Ascophyllum nodosum. The polysaccharide contained L-fucose and sulfate as the only constituents. Combination of methylation analysis, Smith degradation, FTIR and NMR spectroscopy on the native and the de-sulfated polymers demonstrated that the fucoidan consisted of a highly branched core region with ...
Marais, M.F., Joseleau, J.P.
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