Results 81 to 90 of about 17,367 (263)

Gut Enterococcus faecium derived leucic acid mediates the antiobesity effect of dietary fiber

open access: yesiMeta, EarlyView.
This study identified Enterococcus faecium as a gut bacterium with anti‐obesity activity, which alleviated adipocyte hypertrophy, dyslipidemia, and hepatic steatosis by converting leucine into leucic acid (LEA) to regulate mitochondrial oxidative phosphorylation.
Baifei Hu   +9 more
wiley   +1 more source

Fucoidan Alleviates Intestine Damage in Mice Induced by LPS via Regulation of Microbiota

open access: yesPakistan Veterinary Journal
Fucoidan is a popular polysaccharide known to have important biological functions.In the present research, the therapeutic effect of fucoidan on gastrointestinal illness induced by lipopolysaccharide (LPS) in mice was determined.A total of thirty ICR ...
Song Peng   +9 more
semanticscholar   +1 more source

Recent Advances in Cryogel Applications for Musculoskeletal Regeneration

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Hydrogels have been widely used in tissue engineering due to their high‐water content and biocompatibility, yet their densely cross‐linked microstructure inherently limits cell infiltration, mass transport, and mechanical support. Cryogels, formed through partial freezing and crosslinking under subzero conditions, provide unique 3D macroporous
Dohee Kim   +4 more
wiley   +1 more source

Fucoidan Induces Apoptosis of HT-29 Cells via the Activation of DR4 and Mitochondrial Pathway

open access: yesMarine Drugs, 2020
Fucoidan has a variety of pharmacological activities, but the understanding of the mechanism of fucoidan-induced apoptosis of colorectal cancer cells remains limited.
Xu Bai   +6 more
doaj   +1 more source

Plant‐Derived Natural Product Nanodelivery System in Cancer Therapy

open access: yesPhytotherapy Research, EarlyView.
This review comprehensively summarizes the recent progress and emerging concepts in nanotechnology‐based delivery systems for plant‐derived natural products, with a particular focus on their application in precision cancer therapy. ABSTRACT Plant‐derived natural products have emerged as important sources of anticancer agents because of their diverse ...
Changqi Shi   +9 more
wiley   +1 more source

The Origin, Properties, Structure, Catalytic Mechanism, and Applications of Fucoidan-Degrading Enzymes

open access: yesMarine Drugs
Fucoidanase is a class of enzymes capable of hydrolyzing fucoidan, a complex sulfated polysaccharide found mainly in marine brown algae and some marine invertebrates.
Yi Zhao   +5 more
doaj   +1 more source

Comparative Study of Fucoidan from Saccharina japonica and Its Depolymerized Fragment on Adriamycin-Induced Nephrotic Syndrome in Rats

open access: yesMarine Drugs, 2020
Nephrotic syndrome (NS) is a clinical syndrome with a variety of causes, mainly characterized by heavy proteinuria, hypoalbuminemia, and edema. At present, identification of effective and less toxic therapeutic interventions for nephrotic syndrome ...
Jiaojiao Tan   +5 more
doaj   +1 more source

A critical review on extraction, characteristics, physicochemical activities, potential health benefits, and industrial applications of fucoidan

open access: yeseFood, 2022
Fucoidan is a kind of sulfated polysaccharide that consists mainly of fucose and is found in marine brown alga. Fucoidan is a major bioactive compound in brown seaweeds known to have biological activities including anticancer, anti‐inflammatory ...
Bin Du   +6 more
doaj   +1 more source

Natural Polysaccharides for Rheumatoid Arthritis Therapy: Mechanism, Drug Delivery and Clinical Application

open access: yesPhytotherapy Research, EarlyView.
Schematic overview of the experimental models, therapeutic mechanisms, drug delivery systems, and clinical potential of natural polysaccharides in rheumatoid arthritis. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis.
Luxin Li   +14 more
wiley   +1 more source

Metals Influence Structure and Solubility of Fucoidan and Strategy of Metal Removal in Fucoidan

open access: yes, 2021
Undaria pinnatifida is a widely distributed species of brown seaweed in New Zealand. Fucoidan is a sulfated polysaccharide which is extracted from U. pinnatifida. Its numerous bioactivities have been studied for several decades.
Luo, Xuegeng
core  

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