Results 61 to 70 of about 7,540 (179)
Food Safety and Health, EarlyView.In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso +3 more
wiley +1 more source
Marine Drugs, 2020 Nephrotic syndrome (NS) is a clinical syndrome with a variety of causes, mainly characterized by heavy proteinuria, hypoalbuminemia, and edema. At present, identification of effective and less toxic therapeutic interventions for nephrotic syndrome ...
Jiaojiao Tan +5 more
doaj +1 more source
Natural Products as Modulators of ABC Transporters in Breast Cancer
Phytotherapy Research, EarlyView.ABSTRACT Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple‐negative breast cancer (TNBC), continues to hinder effective therapy.
Yoganishalini Sagadevan +2 more
wiley +1 more source
Journal of Animal Physiology and Animal Nutrition, EarlyView.ABSTRACT While β‐glucans from plants and yeasts have been extensively studied in weaned piglets, studies examining algae β‐glucans are scarce. Thus, the present study aimed to examine the effects of feeding algae β‐glucan in weaned piglets. Male, 21‐day‐old, weaned crossbred piglets were allotted to three experimental groups, which were fed either an ...
Johanna O. Buckenberger +7 more
wiley +1 more source
Fucoidan can function as an adjuvant in vivo to enhance dendritic cell maturation and function and promote antigen-specific T cell immune responses. [PDF]
PLoS ONE, 2014 Fucoidan, a sulfated polysaccharide purified from brown algae, has a variety of immune-modulation effects, including promoting antigen uptake and enhancing anti-viral and anti-tumor effects.
Jun-O Jin +5 more
doaj +1 more source
Fucoidan-Supplemented Diet Potentiates Immune Checkpoint Blockage by Enhancing Antitumor Immunity
Frontiers in Cell and Developmental Biology, 2021 Immune checkpoint blockade (ICB) therapies such as PD-1 antibodies have produced significant clinical responses in treating a variety of human malignancies, yet only a subset of cancer patients benefit from such therapy.
Juan Yang +21 more
doaj +1 more source
Engineering Reports, Volume 8, Issue 6, June 2026.A pseudo‐two‐dimensional (P2D) reaction–diffusion framework is proposed to model reactive oxygen species (ROS) generation, transport, and scavenging in Ag–ZnO/Fucoidan nanocomposites. Spatially segregated ROS source (Ag–ZnO) and sink (fucoidan) domains are embedded into a one‐dimensional computational model, capturing nonlinear feedback between site ...
Mohamed Abu Shuheil +8 more
wiley +1 more source
Oral fucoidan improves muscle size and strength in mice
Physiological Reports, 2021 Fucoidan is a sulfated polysaccharide found in a range of brown algae species. Growing evidence supports the long‐term supplementation of fucoidan as an ergogenic aid to improve skeletal muscle performance.
Sally E. McBean +8 more
doaj +1 more source
Acute Lung Injury: From Molecular Circuits to System‐Level Therapeutics
MedComm, Volume 7, Issue 6, June 2026.This visual summary illustrates the paradigm shift from linear pathways to network medicine in ALI. Three interconnected circuits—innate immunity, immunometabolism, and cell death (PANoptosis)—drive disease progression under multiorgan crosstalk (gut–lung, brain–lung).
Yaoli Hou +10 more
wiley +1 more source
British Journal of Haematology, Volume 208, Issue 6, Page 1965-1979, June 2026.Summary ETV6‐related thrombocytopenia (ETV6‐RT) is an inherited platelet disorder caused by germline ETV6 variants. Despite recent progress, the mechanisms underlying platelet dysfunction in ETV6‐RT remain unclear. We investigated 12 patients from six families using functional assays, electron microscopy, quantitative proteomics and cytoskeletal ...
Ivan P. Tesakov +15 more
wiley +1 more source