Holothurian fucosylated chondroitin sulfate. [PDF]
Mar Drugs, 2014 Fucosylated chondroitin sulfate (FucCS) is a structurally distinct glycosaminoglycan found in sea cucumber species. It has the same backbone composition of alternating 4-linked glucuronic acid and 3-linked N-acetyl galactosamine residues within ...
Pomin VH.
europepmc +2 more sources
Structure and Anti-Inflammatory Activity of a New Unusual Fucosylated Chondroitin Sulfate from Cucumaria djakonovi. [PDF]
Mar Drugs, 2018 Fucosylated chondroitin sulfate CD was isolated from the sea cucumber Cucumaria djakonovi collected from the Avachinsky Gulf of the eastern coast of Kamchatka.
Ustyuzhanina NE +9 more
europepmc +2 more sources
Fucosylated chondroitin sulfate inhibits Plasmodium falciparum cytoadhesion and merozoite invasion. [PDF]
Antimicrob Agents Chemother, 2014 Sequestration of Plasmodium falciparum-infected erythrocytes (Pf-iEs) in the microvasculature of vital organs plays a key role in the pathogenesis of life-threatening malaria complications, such as cerebral malaria and malaria in pregnancy.
Bastos MF +14 more
europepmc +3 more sources
In Vivo Anti-Cancer Mechanism of Low-Molecular-Weight Fucosylated Chondroitin Sulfate (LFCS) from Sea Cucumber Cucumaria frondosa. [PDF]
Molecules, 2016 The low-molecular-weight fucosylated chondroitin sulfate (LFCS) was prepared from native fucosylated chondroitin sulfate (FCS), which was extracted and isolated from sea cucumber Cucumaria frondosa, and the anti-cancer mechanism of LFCS on mouse Lewis ...
Liu X +9 more
europepmc +2 more sources
Programmable Enzymatic Toolbox for the Assembly of Fucosylated Chondroitin Derivatives
, 2023 Fucosylated chondroitin sulfate (FuCS), a unique glycosaminoglycan derived from the body walls of sea cucumbers, plays a vital role in various physiological processes.
Changcheng Liu (381699) +9 more
core +1 more source
Chemical Synthesis of Fucosylated Chondroitin Sulfate Tetrasaccharide with Fucosyl Branch at the 6-OH of GalNAc Residue. [PDF]
Mar DrugsFucosylated chondroitin sulfate is a unique glycosaminoglycan isolated from sea cucumbers, with excellent anticoagulant activity. The fucosyl branch in FCS is generally located at the 3-OH of D-glucuronic acid but, recently, a novel structure with α
Lv C, Li X, Yang G, Chen H, Li C.
europepmc +2 more sources
Nonspecific Immunoglobulin M Binding and Chondroitin Sulfate A Binding Are Linked Phenotypes of Plasmodium falciparum Isolates Implicated in Malaria during Pregnancy [PDF]
, 2003 Binding of immunoglobulin M (IgM) antibodies from normal human serum to the surface of Plasmodium falciparum-infected red blood cells (iRBC) has previously been demonstrated only in parasites that form rosettes with uninfected red cells.
Rowe, J Alexandra; id_orcid +5 more
core +1 more source
Influence of chondroitin 6-sulfate oligosaccharide unit addition on the immunopathogenicity of human thyroglobulin in cba/j(h-2k) mice. Multiple effects on antigen processing and t cell responses [PDF]
, 2006 The site of type D (chondroitin 6-sulfate) oligosaccharide unit addition to human thyroglobulin (hTg) was localized. Furthermore, hTg and its fractions endowed with chondroitin 6-sulfate oligosaccaride units (hTg-CS) and devoid of it (hTg-CS-), were ...
Conte, Marisa
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Reduced molecular size and altered disaccharide composition of cerebral chondroitin sulfate upon Alzheimer’s pathogenesis in mice [PDF]
, 2016 2016-08Alzheimer’s disease (AD) is a progressive disorder leading to cognitive impairment and neuronal loss. Cerebral extracellular accumulation and deposition of amyloid ß plaques is a pathological hallmark of AD.
Zhang, Zui +3 more
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INCREASED CALCIUM AFFINITY OF A FUCOSYLATED CHONDROITIN SULFATE FROM SEA-CUCUMBER
, 1994 Calcium binding and charge distribution on a fucosylated chondroitin sulfate and a standard chondroitin 6-sulfate have been studied using a metallochromic indicator and conductimetric titrations.
Mourao, PAS, Vieira, R. P., Ruggiero, J.
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