Results 31 to 40 of about 1,579 (190)
Marine organism sulfated polysaccharides exhibiting significant antimalarial activity and inhibition of red blood cell invasion by Plasmodium [PDF]
, 2016 The antimalarial activity of heparin, against which there are no resistances known, has not been therapeutically exploited due to its potent anticoagulating activity.
Fernàndez Busquets, Xavier +3 more
core +1 more source
Antiproliferative activity of glycosaminoglycan-like polysaccharides derived from marine molluscs [PDF]
, 2018 Despite the increasing availability of new classes of cancer treatment, such as immuneand targeted therapies, there remains a need for the development of new antiproliferative/cytotoxic drugs with improved pharmacological profiles that can also ...
Gallagher +3 more
core +2 more sources
Biotechnology Journal, Volume 18, Issue 11, November 2023., 2023 Graphical Abstract and Lay Summary Encapsulation of biomolecules with metal organic frameworks has great potential for therapeutic applications. Biomolecule quantification is necessary for efficacy assessment and optimization. There are many techniques for biomolecule quantification.
Joel Yong +5 more
wiley +1 more source
Structural and kinetic analyses of holothurian sulfated glycans suggest potential treatment for SARS-CoV-2 infection [PDF]
, 2021 Certain sulfated glycans, including those from marine sources, can show potential effects against SARS-CoV-2. Here, a new fucosylated chondroitin sulfate (FucCS) from the sea cucumber Pentacta pygmaea (PpFucCS) (MW ∼10.60 kDa) was isolated and ...
Dwivedi, Rohini +3 more
core +2 more sources
The Sea as a Rich Source of Structurally Unique Glycosaminoglycans and Mimetics
Microorganisms, 2017 Glycosaminoglycans (GAGs) are sulfated glycans capable of regulating various biological and medical functions. Heparin, heparan sulfate, chondroitin sulfate, dermatan sulfate, keratan sulfate and hyaluronan are the principal classes of GAGs found in ...
Ariana A. Vasconcelos, Vitor H. Pomin
doaj +1 more source
Food Science and Human Wellness, 2022 Enzymatic hydrolysis has been widely used to produce bioactive hydrolysates from sea cucumber body wall. Here, inspired by the clarification of Apostichopus japonicus genome, we investigated the enzymatic hydrolysis of sea cucumber body wall by using the
Yanchao Wang +5 more
doaj +1 more source
The Chemical Neurobiology of Carbohydrates [PDF]
, 2008 The cell surface displays a complex array of oligosaccharides, glycoproteins, and glycolipids. This diverse mixture of glycans contains a wealth of information, modulating a wide range of processes such as cell migration, proliferation, transcriptional ...
Hsieh-Wilson, Linda C. +1 more
core +1 more source
Galactosaminoglycans: Medical Applications and Drawbacks
Molecules, 2019 Galactosaminoglycans (GalAGs) are sulfated glycans composed of alternating N-acetylgalactosamine and uronic acid units. Uronic acid epimerization, sulfation patterns and fucosylation are modifications observed on these molecules.
Vitor H. Pomin +4 more
doaj +1 more source
Marine Drugs, 2021 Marine organisms are a source of active biomolecules with immense therapeutic and nutraceutical potential. Sulfated fucose-rich polysaccharides are present in large quantities in these organisms with important pharmacological effects in several ...
Roberto J. C. Fonseca +1 more
doaj +1 more source
The sweet branch of metabolic engineering: cherry-picking the low-hanging sugary fruits [PDF]
, 2015 In the first science review on the then nascent Metabolic Engineering field in 1991, Dr. James E. Bailey described how improving erythropoietin (EPO) glycosylation can be achieved via metabolic engineering of Chinese hamster ovary (CHO) cells.
Rachel Chen
core +1 more source