Results 41 to 50 of about 1,579 (190)
Keratan sulfate phenotype in the β-1,3-N-acetylglucosaminyltransferase-7-null mouse cornea [PDF]
, 2018 Purpose: Synthesis of keratan sulfate (KS) relies on coordinated action of multiple enzymes, including the N-acetylglucosamine–transferring enzyme, β-1,3-N-acetylglucosaminyltransferase-7 (β3GnT7).
Akama, T.O. +7 more
core +2 more sources
Marine Drugs, 2022 Fucosylated chondroitin sulfate (FCS) from the sea cucumber Acaudina molpadioides (FCSAm) is the first one that was reported to be branched by disaccharide GalNAc-(α1,2)-Fuc3S4S (15%) and sulfated Fuc (85%).
Weili Wang +6 more
doaj +1 more source
Does Glyphosate Acting as a Glycine Analogue Contribute To ALS? [PDF]
, 2016 Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease involving several protein mutations in glycine-rich regions with limited treatment options.
Hadden, Michael J. +3 more
core +1 more source
Altered glycosylation in progression and management of bladder cancer [PDF]
, 2023 Bladder cancer (BC) is the 10th most common malignancy worldwide, with an estimated 573,000 new cases and 213,000 deaths in 2020. Available therapeutic approaches are still unable to reduce the incidence of BC metastasis and the high mortality rates of ...
core +1 more source
The influence of host genetics on erythrocytes and malaria infection: is there therapeutic potential? [PDF]
, 2015 As parasites, Plasmodium species depend upon their host for survival. During the blood stage of their life-cycle parasites invade and reside within erythrocytes, commandeering host proteins and resources towards their own ends, and dramatically ...
Burgio, Gaetan +3 more
core +4 more sources
Mucin glycosylation and sulphation in airway epithelial cells is not influenced by cystic fibrosis transmembrane conductance regulator expression [PDF]
, 2005 Abnormalities in mucus properties and clearance make a major contribution to the pathology of cystic fibrosis (CF). Our aim was to test the hypothesis that the defects in CF mucus are a direct result of mutations in the CF transmembrane conductance ...
Dell, Anne +6 more
core +1 more source
Marine Drugs, 2022 Fucosylated chondroitin sulfates (FCSs) FCS-BA and FCS-HS, as well as fucan sulfates (FSs) FS-BA-AT and FS-HS-AT were isolated from the sea cucumbers Bohadschia argus and Holothuria (Theelothuria) spinifera, respectively.
Nadezhda E. Ustyuzhanina +11 more
doaj +1 more source
Synthesis of Marine Natural Products and Molecules Inspired by Marine Substances [PDF]
, 2022 Marine natural products are characterized by high chemical diversity, biochemical specificity, and other molecular properties that make them favorable as lead structures for drug discovery.
core +1 more source
Research Progress on Structure, Activity and Structure-Activity Relationship of Sea Cucumber Polysaccharides [PDF]
Shipin KexueThe sea cucumber is an invertebrate with significant economic value and is extensively consumed as a tonic food in Asian countries due to its high nutritional value.
SHU Zhiqiang, LIU Fang, JING Yuexin, JIAO Chunna, JI Yizhi, WANG Maojian, WANG Gongming, ZHANG Jian
doaj +1 more source
Frontiers in Marine Science, 2022 Sea cucumbers are amongst the highest value seafoods available commercially, especially in the south-east Asian region, primarily due to their nutritional and health benefits as applied in Traditional Chinese Medicine.
Qi Liang +11 more
doaj +1 more source