Results 61 to 70 of about 1,579 (190)
A new heparan sulfate from the mollusk nodipecten nodosus inhibits merozoite invasion and disrupts rosetting and cytoadherence of plasmodium falciparum [PDF]
Despite treatment with effective antimalarial drugs, the mortality rate is still high in severe cases of the disease, highlighting the need to find adjunct therapies that can inhibit the adhesion of Pf-iEs.
Albrecht, L. +10 more
core +1 more source
Structural elucidation of fucosylated chondroitin sulfates from sea cucumber using FTICR-MS/MS [PDF]
Fucosylated chondroitin sulfates are complex polysaccharides extracted from sea cucumber. They have been extensively studied for their anticoagulant properties and have been implicated in other biological activities. While nuclear magnetic resonance spectroscopy has been used to extensively characterize fucosylated chondroitin sulfate oligomers, we ...
Isaac Agyekum +7 more
openaire +2 more sources
SUMMARY Pattern recognition receptors (PRRs) function across diverse eukaryotic organisms as a powerful surveillance system to perceive danger signals and to trigger specific adaptive responses. This complex receptor network constitutes the first layer of perception of the innate immune system of plants and mammals.
Gonzalo Vílchez‐Pinto +4 more
wiley +1 more source
Identification of a carbohydrate-based endothelial ligand for a lymphocyte homing receptor. [PDF]
Lymphocyte attachment to high endothelial venules within lymph nodes is mediated by the peripheral lymph node homing receptor (pnHR), originally defined on mouse lymphocytes by the MEL-14 mAb.
Fennie, C +4 more
core
A Further Unique Chondroitin Sulfate from the shrimp Litopenaeus vannamei with Antithrombin Activity that Modulates Acute Inflammation [PDF]
The detailed structure of a further Chondroitin Sulfate from Litopenaeus vannamei shrimp (sCS) is described. The backbone structure was established by 1H/13C NMR, which identified 3-O-sulfated GlcA, 4-O-sulfated GalNAc, 6-O-sulfated GalNAc, and 4,6-di-O ...
Andrade, GPV +8 more
core +2 more sources
Inhibition of SARS-CoV-2 wild-type (Wuhan-Hu-1) and Delta (B.1.617.2) strains by marine sulfated glycans [PDF]
The Coronavirus disease pandemic has steered the global therapeutic research efforts toward the discovery of potential anti-severe acute respiratory syndrome coronavirus (SARS-CoV-2) molecules.
Dwivedi, Rohini +3 more
core +2 more sources
Antiviral activity of marine sulfated glycans against pathogenic human coronaviruses
Great interest exists towards the discovery and development of broad-spectrum antivirals. This occurs due to the frequent emergence of new viruses which can also eventually lead to pandemics.
Mary Zoepfl +4 more
doaj +1 more source
Bacteroides thetaiotaomicron, one of the most eminent representative gut commensal Bacteroides species, is able to use the L-fucose in host-derived and dietary polysaccharides to modify its capsular polysaccharides and glycoproteins through a mammalian ...
Xiao Tian +7 more
doaj +1 more source
This review summarizes the research progress on inhibitors of lumpy skin disease virus (LSDV), focusing on its biological characteristics and key proteins involved in the viral replication cycle. It compiles various inhibitors (direct‐acting poxvirus inhibitors and host‐directed poxvirus inhibitors) against poxviruses, their mechanisms of action, and ...
Leilei ZHAO +7 more
wiley +1 more source
Natural anionic polysaccharides fucosylated chondroitin sulfates (FCS) from sea cucumbers attract great attention nowadays due to their ability to influence various biological processes, such as blood coagulation, thrombosis, angiogenesis, inflammation ...
Nadezhda E. Ustyuzhanina +4 more
doaj +1 more source

