Results 81 to 90 of about 1,579 (190)

Comparison of Physicochemical Characteristics and Anticoagulant Activities of Polysaccharides from Three Sea Cucumbers

Marine Drugs, 2013
In order to search for sulfated polysaccharides in different invertebrate connective tissues and to examine their biological activities, we have isolated three types of polysaccharides from the body wall of the three sea cucumbers Holothuria edulis ...
Shengmin Wang, Na Gao, Chuang Xiao, Feng Lu, Jingying Xiang, Wu Lian, Li Xu, Mingyi Wu, Lan Luo, Jinhua Zhao   +9 more
doaj   +1 more source

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2021–2022

Mass Spectrometry Reviews, Volume 44, Issue 3, Page 213-453, May/June 2025.
Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley   +1 more source

Fucosylated Chondroitin Sulfates from the Sea Cucumbers Paracaudina chilensis and Holothuria hilla: Structures and Anticoagulant Activity

Marine Drugs, 2020
Fucosylated chondroitin sulfates (FCSs) PC and HH were isolated from the sea cucumbers Paracaudina chilensis and Holothuria hilla, respectively. The purification of the polysaccharides was carried out by anion-exchange chromatography on a DEAE-Sephacel ...
Nadezhda E. Ustyuzhanina, Maria I. Bilan, Andrey S. Dmitrenok, Alexandra S. Silchenko, Boris B. Grebnev, Valentin A. Stonik, Nikolay E. Nifantiev, Anatolii I. Usov   +7 more
doaj   +1 more source

Northern Sea Cucumber (Cucumaria frondosa): A Potential Candidate for Functional Food, Nutraceutical, and Pharmaceutical Sector [PDF]

, 2020
Sea cucumber (Cucumaria frondosa) is the most abundant and widely distributed species in the cold waters of North Atlantic Ocean. C. frondosa contains a wide range of bioactive compounds, mainly collagen, cerebrosides, glycosaminoglycan, chondroitin ...
Dave, Deepika, Hossain, Abul, Shahidi, Fereidoon   +2 more
core   +2 more sources

Tumor Glycosylation: A Main Player in the Modulation of Immune Responses

European Journal of Immunology, Volume 55, Issue 3, March 2025.
Cancer cells present aberrant glycosylation patterns that contribute to the evasion of antitumor immunity by triggering lectin receptors. Therefore, tumor glycosylation represents an interesting target for novel immunotherapy strategies. This review discusses the different mechanisms by which tumor‐derived glycans induce tolerogenic programs in immune ...
Ernesto Rodriguez
wiley   +1 more source

Sulfated Glycans Inhibit the Interaction of MERS-CoV Receptor Binding Domain with Heparin

Viruses
Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic virus with high contagion and mortality rates. Heparan sulfate proteoglycans (HSPGs) are ubiquitously expressed on the surface of mammalian cells.
Jiyuan Yang, Yuefan Song, Weihua Jin, Ke Xia, Grace C. Burnett, Wanjin Qiao, John T. Bates, Vitor H. Pomin, Chunyu Wang, Mingqiang Qiao, Robert J. Linhardt, Jonathan S. Dordick, Fuming Zhang   +12 more
doaj   +1 more source

Specific sulfation and glycosylation - a structural combination for the anticoagulation of marine carbohydrates

Frontiers in Cellular and Infection Microbiology, 2014
Based on considered achievements of the last 25 years, specific combinations of sulfation patterns and glycosylation types have been proved to be key structural players for the anticoagulant activity of certain marine glycans.
Vitor Hugo Pomin, Paulo Antonio De Souza Mourão   +1 more
doaj   +1 more source

Genome‐Wide Association Studies of Polysaccharides, Collagen, and Saponin Traits in the Sea Cucumber Apostichopus japonicus

Aquaculture Research, Volume 2025, Issue 1, 2025.
Apostichopus japonicus is a commercially important marine species known for its high nutritional value and a range of bioactive compounds, including polysaccharides, collagen, and saponins. In this study, a genome‐wide association study (GWAS) was carried out on 143 A. japonicus individuals.
Yongjie Wang, Xianglei Zhang, Shufeng Li, Ye Tian, Weiyan Li, Qi Ye, Fenglin Tian, Haoran Xiao, Junhui Wang, Wanrong Tian, Hao Wang, Yangqing Chang, Chong Zhao, Luo Wang, Lingshu Han, Jun Ding   +15 more
wiley   +1 more source

Glycosylation of a CNS-specific extracellular matrix glycoprotein, tenascin-R, is dominated by O-linked sialylated glycans and "brain-type” neutral N-glycans [PDF]

, 2017
As a member of the tenascin family of extracellular matrix glycoproteins, tenascin-R is located exclusively in the CNS. It is believed to play a role in myelination and axonal stabilization and, through repulsive properties, may contribute to the lack of
Dwek, Raymond A., Harvey, David J., Mattu, Taj S., Pesheva, Penka, Schachner, Melitta, Wing, David R., Zamze, Susanne   +6 more
core  

A biological guide to glycosaminoglycans: current perspectives and pending questions

The FEBS Journal, Volume 291, Issue 15, Page 3331-3366, August 2024.
Mammalian glycosaminoglycans, except hyaluronan, are sulfated polysaccharides that are covalently attached to core proteins to form proteoglycans. They contribute to the organization of the extracellular matrix and are displayed at the cell surface where they regulate the availability and activity of cytokines and growth factors and cell signaling ...
Sylvie Ricard‐Blum, Romain R. Vivès, Liliana Schaefer, Martin Götte, Rosetta Merline, Alberto Passi, Paraskevi Heldin, Ana Magalhães, Celso A. Reis, Spyros S. Skandalis, Nikos K. Karamanos, Serge Perez, Dragana Nikitovic   +12 more
wiley   +1 more source