Results 91 to 100 of about 1,579 (190)

Isolation and composition analysis of bioactive glycosaminoglycans from whelk [PDF]

open access: yes, 2018
Glycosaminoglycans (GAGs) are found covalently attached to proteins, which create conjugates known as proteoglycans. GAGs have remarkable biological activity as co-receptors for a variety of growth factors, cytokines, and chemokines.
Khurshid, CA, Pye, DA
core   +2 more sources

Postoperative tumor treatment strategies: From basic research to clinical therapy

open access: yesVIEW, Volume 5, Issue 3, June 2024.
The latest research on the molecular mechanism of tumor and clinical treatment for postoperative recurrence of tumors has been introduced. This review focuses on the emerging technologies used for postoperative tumor treatment in recent years in terms of functional classification. Abstract Despite progression in advanced treatments for malignant tumors,
Minna Xiao   +7 more
wiley   +1 more source

Sea Cucumbers Metabolites as Potent Anti-Cancer Agents

open access: yesMarine Drugs, 2015
Sea cucumbers and their extracts have gained immense popularity and interest among researchers and nutritionists due to their nutritive value, potential health benefits, and use in the treatment of chronic inflammatory diseases.
Naveena B. Janakiram   +2 more
doaj   +1 more source

Comparative proteomic profiling of the serum differentiates pancreatic cancer from chronic pancreatitis [PDF]

open access: yes, 2017
Finland ranks sixth among the countries having highest incidence rate of pancreatic cancer with mortality roughly equaling incidence. The average age of diagnosis for pancreatic cancer is 69years in Nordic males, whereas the average age of diagnosis of ...
Ahmed   +42 more
core   +1 more source

Molecular analysis of the extracellular microenvironment: from form to function

open access: yesFEBS Letters, Volume 598, Issue 6, Page 602-620, March 2024.
This review provides a thorough background on the complex structure and function of the major proteins in the extracellular proteome. Analytical challenges that result from these complex structures are detailed followed by current techniques and strategies for spatially profiling the extracellular microenvironment.
Jade K. Macdonald   +3 more
wiley   +1 more source

Fucosylated and Sulfated Glycans Investigated using Cryogenic Infrared Spectroscopy [PDF]

open access: yes, 2022
Unusual monosaccharides (fucose), covalent modifications of glycans (sulfation) and terminal sequences play important biological roles in physiology and pathology of living organisms.
Lettow, M.
core  

Glycomic Analysis of Biomedically Important O-glycoconjugates

open access: yes, 2011
It has been established that all cells carry an array of glycans attached to proteins and lipids that are crucial in the interaction between cells and the surrounding matrix. Proteins are mainly glycosylated on asparagines (N-glycosylation) and serine or
Ismail, Mohd Nazri, Ismail, Mohd Nazri
core   +1 more source

Macro insights into the shared and distinct regulations of dietary polysaccharides on gut microbiota and their roles in obesity

open access: yesFood Safety and Health, Volume 2, Issue 1, Page 4-20, January 2024.
This review comprehensively summarizes the latest findings regarding the sources and structural characteristics of dietary polysaccharides (pectic polysaccharides, sulfated polysaccharides, glucan‐like polysaccharides, and fructan‐like polysaccharides), their shared and distinct effects on gut microbiota and associated metabolites, and the consequent ...
Zhiqing Xie   +7 more
wiley   +1 more source

Extraction, Physicochemical Properties, and In Vitro Antioxidant Activities of Chondroitin Sulfate from Bovine Nose Cartilage

open access: yesInternational Journal of Food Science, Volume 2024, Issue 1, 2024.
Beef is an important high‐nutrition livestock product, and several byproducts, such as bovine cartilage, are produced during slaughter. To effectively utilize these agricultural and pastoral byproducts, combined (trypsin‐papain) enzymolysis and cetylpyridine chloride purification methods were used to obtain chondroitin sulfate (CS) from the nasal ...
Chan Shi   +6 more
wiley   +1 more source

Perspective on the Use of Sulfated Polysaccharides from Marine Organisms as a Source of New Antithrombotic Drugs

open access: yesMarine Drugs, 2015
Thromboembolic diseases are increasing worldwide and always require anticoagulant therapy. We still need safer and more secure antithrombotic drugs than those presently available. Sulfated polysaccharides from marine organisms may constitute a new source
Paulo A. S. Mourão
doaj   +1 more source

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