Targeting fucosyltransferase FUT8 as a prospective therapeutic approach for DLBCL
OncogenesisDiffuse large B-cell lymphoma (DLBCL) is characterized by its aggressive nature and resistance to standard chemotherapy, necessitating the development of new therapeutic approaches.
Hao Xu +9 more
doaj +1 more source
Molecular Cloning and Expression of a Third Type of Rabbit GDP-L-Fucose:β-D-Galactoside 2-α-L-Fucosyltransferase [PDF]
, 1996 Seiji Hitoshi +3 more
openalex +1 more source
IgG Fucosylation: An Emerging Key Player in the Treatment of Severe COVID-19
EngineeringProtein glycosylation is one of the most vital modifications. Understanding the role of protein glycosylation in coronavirus disease 2019 (COVID-19) is the key in elucidating its pathogenesis and developing therapeutic strategies.
Caiping Zhao +11 more
doaj +1 more source
Biological Research, 2011 The Notch signaling pathway plays an important role in development and physiology. In Drosophila, Notch is activated by its Delta or Serrate ligands, depending in part on the sugar modifications present in its extracellular domain. O-fucosyltransferase-1
Alvaro Glavic +2 more
doaj
Inhibition of fucosyltransferase VII by gallic acid and its derivatives
, 2004 Xiaoda Niu +5 more
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Isolation and characterization of murine alpha(1 going to 3)fucosyltransferase genes. [PDF]
, 1995 Murine $\alpha(1\to3$)fucosyltransferase genes provide the means to understand the function of $\alpha(1\to3$)fucosylated glycoconjugates during development and in the adult animal. Towards this end, we have isolated two murine genes which encode enzymes
Gersten, Kevin Michael
core
Downregulation of microRNA-15b by hepatitis B virus X enhances hepatocellular carcinoma proliferation via fucosyltransferase 2-induced Globo H expression. [PDF]
, 2014 [[abstract]]Globo H, a cancer-associated carbohydrate antigen, is highly expressed in various types of cancers. However, the role of Globo H in hepatocellular carcinoma (HCC) remains elusive.
Wu, CS;Wu, CS;Yen, CJ;Yen, CJ;鄒瑞煌;Chou, Ruey-Hwang;Chen, JN;Chen, JN;Huang, WC;Huang, WC;Wu, CY;Wu, CY;余永倫
core +2 more sources
Quantitative changes of fucosylated human milk oligosaccharides during lactation in comparison to milk fucosyltransferase activity [PDF]
Human milk contains 7-20 g/L of free oligosaccharides. The oligosaccharides show large variations in size and structure. It has been suggested that milk oligosaccharides can prevent pathogenic microorganisms from attaching to the gastrointestinal ...
Lundblad, Arne, +2 more
core
Molecular Cloning, Expression, Chromosomal Assignment, and Tissue-specific Expression of a Murine α-(1,3)-Fucosyltransferase Locus Corresponding to the Human ELAM-1 Ligand Fucosyl Transferase [PDF]
, 1995 Kevin M. Gersten +9 more
openalex +1 more source
Smoking and polymorphisms of fucosyltransferase gene Le affect success of H. pylori eradication with lansoprazole, amoxicillin, and clarithromycin [PDF]
, 2003 Keitaro Matsuo +7 more
openalex +1 more source