Results 221 to 230 of about 5,422 (250)

Core Tri-fucosylation of Nematode N-glycans Requires Golgi α-mannosidase III Activity that Impacts Animal Growth and Behaviours

Kendler J, Wöls F, Thapliyal S, Arcalis E, Gabriel H, Kubitschek S, Malzl D, Strobl MR, Palmberger D, Luber T, Unverzagt C, Paschinger K, Glauser DA, Wilson IBH, Yan S.   +14 more
europepmc   +1 more source

Development of fucosyltransferase inhibitors

, 2002
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ChemInform Abstract: Development of Fucosyltransferase and Fucosidase Inhibitors [PDF]

ChemInform, 2013
AbstractReview: 100 refs.
Chun-Hung Lin, Chun-Hung Lin, Yu-Nong Lin, Zhijay Tu   +3 more
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The polymorphisms of fucosyltransferases

Legal Medicine, 2001
The alpha(1,2)fucosyltransferase Se enzyme regulates the expression of the ABH antigens in secretion. Secretors, who have ABH antigens in their saliva, have at least one functional Se allele in the FUT2 locus, while non-secretors, who fail to express ABH antigens in saliva, are homozygous for the non-functional se allele. Molecular analyses of the FUT2
Hiroshi Kimura, Yoshiro Koda, Mikiko Soejima   +2 more
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Evaluation of serum fucosyltransferases in malignancy

European Journal of Cancer and Clinical Oncology, 1984
Incorporation of [14C]-fucose into the endogenous acceptor of serum and into the exogenous acceptors desialofetuin (alpha 2-fucosyltransferase) and desialodegalactofetuin (alpha 3-fucosyltransferase) was determined in controls and in patients with various malignant diseases.
R. Kuzmits, Aiginger P
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Characterization of fucosyltransferase activity during mouse spermatogenesis: evidence for a cell surface fucosyltransferase

Biochemistry, 1989
Fucosyltransferase activity was quantified in mouse germ cells at different stages of spermatogenesis. Specifically, fucosyltransferase activities of pachytene spermatocytes, round spermatids, and cauda epididymal sperm were compared. Fucosyltransferase activity of mixed germ cells displayed an apparent Vmax of 17 pmol (mg of protein)-1 min-1 and an ...
D.R. Armant, Richard A. Cardullo, C.F. Millette   +2 more
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Fucosyltransferase (α1,2/ α1,3/ α1,4-fucosyltransferases)

2009
Many studies using monoclonal antibodies have demonstrated that fucosylated carbohydrate chains are involved in various physiological functions including development, neuronal activity, and cancerous transformation. The genes encoding fucosyltransferases which synthesize fucosylated carbohydrate antigens have been cloned, and their function has been ...
Takashi Kudo, Hisashi Narimatsu
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Cloning of a rat alpha1,3-fucosyltransferase gene: a member of the fucosyltransferase IV family.

Glycoconjugate journal, 1997
We report the cloning of a rat alpha1,3-fucosyltransferase gene (rFuc-T), isolated from a rat genomic library by a PCR-cross-hybridization based cloning approach using primers derived from the conserved region of human alpha1,3-Fuc-T sequences. Comparison of the rFuc-T predicted amino acid sequence with those of previously cloned human and murine ...
Robert H. McCluer, Frances I. Smith, Elizabeth M. Sajdel-Sulkowska, Gherman Ya Wiederschain   +3 more
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Occurrence and specificities of α3-fucosyltransferases

The Histochemical Journal, 1992
The Le(x) (CD15) carbohydrate antigen and sialylated and oligomeric derivatives thereof have been implicated in cell adhesion processes. Expression of these antigens is developmentally regulated and (re)occurrence of several members of this group has been reported in malignant transformation of cells.
T.J. de Vries, D. H. Van Den Eijnden
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Study of the Fucosyltransferase System in Intestinal Microsomes

Enzyme, 1988
Fucosyltransferase activity of rat small intestine microsomes is solubilized by 0.5% Triton X-100. The solubilized activity can be purified up to 8,300-fold using DEAE-cellulose and affinity chromatography on GDP-Sepharose. At this step, chromatography on Sephadex G15 separates different specificities: N-acetylglucosaminide-alpha-(1,3 ...
Richard M, A. Martin, Broquet P, Louisot P, Biol Mc   +4 more
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