Results 61 to 70 of about 5,697,993 (289)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Multiscale simulation approach to investigate the binder distribution in catalyst layers of high-temperature polymer electrolyte membrane fuel cells

open access: yesScientific Reports, 2022
A multiscale approach involving both density functional theory (DFT) and molecular dynamics (MD) simulations was used to deduce an appropriate binder for Pt/C in the catalyst layers of high-temperature polymer electrolyte membrane fuel cells.
Sung Hyun Kwon   +5 more
doaj   +1 more source

BZ-BattExt – DMFC as Battery-Extender in solar-boat application [PDF]

open access: yes, 2011
For special applications Direct Methanol Fuel Cells (DMFC) are close to commercial application or already commercialized today. However for the step from laboratory to a broader market of fuel cells, a significant cost reduction, as well as an ...
Krajinovic, Katica   +9 more
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Flexible Multiple Micro Sensor for Local Persistent Effect Test in High Temperature Proton Exchange Membrane Fuel Cell Stack

open access: yesInternational Journal of Electrochemical Science, 2017
The nonuniformity of local temperature, voltage and current in the high temperature proton exchange membrane fuel cell stack can accelerate the aging of membrane electrode assembly (MEA) and the failure of overall fuel cell stack.
Chi-Yuan Lee   +6 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Electrochemical Performance and Long-Term Durability of a Reversible Solid Oxide Fuel Cell

open access: yesInternational Journal of Electrochemical Science, 2015
A reversible solid oxide fuel cell (RSOFC) is one system, which is capable of carrying out energy storage and power generation. In the electrolysis mode, an RSOFC acts as solid oxide electrolysis cell (SOEC), producing hydrogen (from water).
Guo-Bin Jung   +10 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Lithium-ion Battery Module Temperature Monitoring by Using Planer Home-Made Micro Thermocouples

open access: yesInternational Journal of Electrochemical Science, 2013
The battery management system is important to the safety of lithium-ion batteries. Safety is determined from the increase in temperature during operation. A traditional thermocouple is too large to insert in a lithium-ion battery module.
Shuo-Jen Lee   +7 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

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