Results 51 to 60 of about 10,509 (217)

Vorinostat Potentiates Chemoimmunotherapy in Immune‐Enriched Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Immune‐enriched pancreatic cancer does not confer a significant survival advantage. SAHA sensitizes these “hot” tumors to chemoimmunotherapy by disrupting a FASN/PARP9‐driven “metabolic trap” and enhancing CD8+ T cell function. A CD8high/FASNhigh/PARP9high signature identifies patients who are most likely to benefit from the “gemcitabine‐nivolumab‐SAHA”
Chen Chen   +13 more
wiley   +1 more source

A Dual‐Functional Biohybrid Nanorobot to Synergistically Eradicate Biofilm and Degrade Antibiotic Resistance Genes

open access: yesAdvanced Science, EarlyView.
A biohybrid nanorobot integrating lytic bacteriophage N4 with Pd nanozymes is developed for targeted eradication of multidrug‐resistant E. coli biofilms. Synergistic bacterial lysis and ROS‐mediated oxidation enable simultaneous biofilm removal and antibiotic resistance genes degradation, maintaining high efficacy in complex wastewater environments ...
Junzheng Zhang   +9 more
wiley   +1 more source

Fuel–Coolant Interaction Visualization Test for In-Vessel Corium Retention External Reactor Vessel Cooling (IVR-ERVC) Condition

open access: yesNuclear Engineering and Technology, 2016
A visualization test of the fuel–coolant interaction in the Test for Real cOrium Interaction with water (TROI) test facility was carried out. To experimentally simulate the In-Vessel corium Retention (IVR)- External Reactor Vessel Cooling (ERVC ...
Young Su Na   +3 more
doaj   +1 more source

Evaluation of fuel load following fire in Loblolly Pine (Pinus taeda L.) plantations using line sampling and of FLM method (Case study: Takhsam plantations in Guilan Province) [PDF]

open access: yesتحقیقات جنگل و صنوبر ایران, 2015
The occurrence of fire in natural ecosystems depends on the prevailing meteorological conditions, the availability of ignition material and the quantity and characteristics of fuel biomass.
Masoud Amin Amlashi   +5 more
doaj   +1 more source

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

open access: yesAdvanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao   +25 more
wiley   +1 more source

Gamma-ray measurement for classification of fuel debris and waste [PDF]

open access: yesEPJ Web of Conferences
The detection of prompt fission gamma-rays and Tl-208 decay gamma-rays, which are unique to nuclear materials, could be applied to sorting nuclear fuel debris and radioactive waste from the Fukushima Daiichi Nuclear Power Plant.
Shiba Tomooki   +2 more
doaj   +1 more source

GLS1 Orchestrates Exosome‐Mediated Tumor‐Endothelial Communication to Facilitate Angiogenesis

open access: yesAdvanced Science, EarlyView.
This study reveals a previously unappreciated, non‐metabolic function of GLS1 in the control of tumor angiogenesis via exosome‐mediated CAV1‐TNC signaling, indicating that therapeutic targeting of GLS1 may offer a dual benefit by simultaneously suppressing tumor metabolic activity and angiogenic processes in head and neck cancer. ABSTRACT Glutaminase 1
Jianqiang Yang   +9 more
wiley   +1 more source

Characteristics of debris resulting from simulated molten fuel coolant interactions in SFRS

open access: yesNuclear Engineering and Technology
Sodium cooled Fast Reactors (SFR) are built with several engineered safety features and hence a severe accident such as a core melt accident is hypothetical with a probability of
E. Hemanth Rao   +3 more
doaj   +1 more source

An Embodied Paper‐Based Microfluidic Al‐Air Battery for Enduring Untethered Insect‐Scale Robots

open access: yesAdvanced Science, EarlyView.
This work presents a centimeter‐scale microfluidic aluminum–air battery (MFAAB) with dual‐surface anode and F−‐mediated byproduct decomposition. The design enables a high capacity of 2697.05 mAh/g Al and delivers tens of milliwatts to power LEDs, motors, and a toy car.
Yun Yang   +5 more
wiley   +1 more source

Experimental study on controlling factors reducing hydrogen concentration in a simulated fuel debris storage container using passive autocatalytic recombiner

open access: yesJournal of Thermal Science and Technology
In the decommissioning work of Tokyo Electric Power Company Holdings Fukushima Daiichi nuclear power plant, the water contained in the fuel debris is radiolyzed when the fuel debris containing water is taken out from the bottom of the reactor vessel and ...
Gaku TAKASE, Kazuyuki TAKASE
doaj   +1 more source

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