Results 31 to 40 of about 97,348 (264)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Production of Hydrogen from Biomass with Negative CO2 Emissions Using a Commercial-Scale Fluidized Bed Gasifier

open access: yesEnergies
Biomass gasification, as a thermochemical method, has attracted interest due to the growing popularity of biofuel production using syngas or pure hydrogen. Additionally, this hydrogen production method, when integrated with CO2 capture, may have negative
Tomasz Chmielniak   +4 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Production of SNG from Biomass Using a Commercial-Scale Fluidized Bed Gasifier Integrated with Water Electrolysis

open access: yesEnergies
Biomass gasification, as a thermochemical process, has attracted growing interest due to the increasing popularity of biofuel production based on syngas or pure hydrogen.
Tomasz Marcin Chmielniak   +4 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Evaluations of Fuel and Air Flow Distributing Qualities within SOFC Stack Designs with Flow Manifolds Penetrated Through Cell Plane

open access: yesInternational Journal of Electrochemical Science, 2017
In order to achieve simply manufacturing process and higher volumetric power density, many planar SOFC stacks were designed to place fuel and air manifolds within the cell unit area and penetrated it.
Shichuan Su   +5 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Effect of gas flow channel structure on the performance of an anode-supported honeycomb solid oxide fuel cell

open access: yesNihon Kikai Gakkai ronbunshu, 2018
An anode-supported honeycomb SOFC gives high volumetric power density and improves thermo-mechanical durability at high temperatures. We have so far fabricated and tested a honeycomb cell with a cathode layer of LSM and an electrolyte layer of 8YSZ on a ...
Hironori NAKAJIMA   +2 more
doaj   +1 more source

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