Results 121 to 130 of about 11,216,273 (301)

Aeroelastic Deformation: Adaptation of Wind Tunnel Measurement Concepts to Full-Scale Vehicle Flight Testing [PDF]

, 2005
The adaptation of a proven wind tunnel test technique, known as Videogrammetry, to flight testing of full-scale vehicles is presented. A description is presented of the technique used at NASA's Dryden Flight Research Center for the measurement of the ...
Burner, Alpheus W., Barrows, Danny A., Lokos, William A.   +2 more
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

The wind tunnels of the national full-scale aerodynamics complex [PDF]

, 1988
A brief overview is given of the National Full-scale Aerodynamics Complex.
Moon, John
core  

Research on multi-chip simultaneous testing method for field programmable gate arrays

Dianzi Jishu Yingyong
With the development of ultra-large scale FPGA chip technology, the number of chip pins has increased to over 1 000. How to achieve efficient testing of ultra-large scale multi-pin FPGA chips has become a challenge for ATE online testing.
Qin Lijun, Yu Yongtao, Luo Jun, Li Junqiu, Pang Shuiquan   +4 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Predicting underwater radiated noise of a full scale ship with model testing and numerical methods

, 2018
Full scale measurement, model testing and a hybrid CFD method were used to characterize the Underwater Radiated Noise (URN) of a ship at design speed.
Torbjörn Johansson, Da-Qing Li, Hallander, Jan,, Jan Hallander, Li, Da-Qing,, Johansson, Torbjörn,   +5 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

ACE-Mat : medium- and full-scale testing over weak soils

The US Army lacks the capability to rapidly repair and upgrade damaged roads along mobility corridors in contested, complex environments. Damaged low-volume roads are often encountered in military operational scenarios for transporting troops, supplies ...
Lulu Edwards, April Bowman, John Rushing, Landon Rhodes, Landon Bull, Donald Embry, Haley Bell   +6 more
core   +1 more source

The Community Readiness Instrument: A Quantitative Measurement Using Statistical Best Practices to Assess Systemic Change Readiness

Behavioral Sciences
Background: Community readiness assessment is used to gauge a community’s ability to address systemic issues and inform action. The Community Readiness Instrument (CRI) is the only published tool to have undergone rigorous development and testing.
Natalie M. Ricciutti, Jenny L. Cureton, Sijia Zhang   +2 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source