Results 101 to 110 of about 11,216,273 (301)

Full-Scale Testing of Precast Concrete Bridge Using Internal Connector in Negative Moment Region

open access: yesAdvances in Civil Engineering, 2019
Conventional concrete marine structures are difficult to construct on site and can cause pollution of the environment. Therefore, concrete marine structures require the development of methods that can minimize the amount of construction that needs to be ...
Heeyoung Lee, Junki Min, Wonseok Chung
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Comparison of experimental vibration characteristics obtained from a 1/5-scale model and from a full-scale saturn sa-1 [PDF]

open access: yes, 1964
Vibrational testing of scale model and full scale Saturn I /SA-1/ launch ...
Catherine, J. J., Mixson, J. S.
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Implications of the Baltimore Rail Tunnel Fire for Full-Scale Testing of Shipping Casks [PDF]

open access: yes, 2003
The U.S. Nuclear Regulatory Commission (NRC) does not currently require full-scale physical testing of shipping casks as part of its certification process. Stakeholders have long urged NRC to require full-scale testing as part of certification.
Dilger, F., Halstead, R. J.
core  

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

High-resolution mechanical characterization of lacustrine shale oil reservoir in China based on scratch testing

open access: yesEnergy Geoscience
The lacustrine shale oil reservoirs in China exhibit pronounced heterogeneity and anisotropy. Conventional approaches for characterizing shale mechanical properties—such as plug-scale mechanical testing and log-derived elastic estimates—provide only ...
Muyang Zhang   +3 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

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