Results 101 to 110 of about 2,779,069 (311)

Full-Scale Testing of Precast Concrete Bridge Using Internal Connector in Negative Moment Region

Advances in Civil Engineering, 2019
Conventional concrete marine structures are difficult to construct on site and can cause pollution of the environment. Therefore, concrete marine structures require the development of methods that can minimize the amount of construction that needs to be ...
Heeyoung Lee, Junki Min, Wonseok Chung
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Phased Array Ultrasonic Testing (PA-UT) Feasibility Study on Pressurized Full Scale Primary Loop Nuclear Piping Mockups

e-Journal of Nondestructive Testing

Brian Hohmann, James J. Wall, Robert Raimondi   +2 more
doaj   +1 more source

Detailed modal testing of a solid rocket motor using a portable test system [PDF]

Modern analytical techniques have expended the ability to evaluate solid rocket motors used in launch vehicles. As more detailed models of solid rocket motors were developed, testing methods were required to verify the models. Experimental modal analysis
Brillhart, Ralph D., Glozman, Vladimir
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Novel Methodological Approach to Developing Scaled-Down Concrete Material for Structural Applications: Experimental Validation Using Froude Scaling

Buildings
Full-scale structural experiments significantly contribute to understanding reinforced concrete (RC) behavior but are often constrained by high costs, extensive time requirements, and practical spatial limitations.
Abdelmoneim El Naggar, Ahmed Soliman, Maged A. Youssef, Hany El Naggar   +3 more
doaj   +1 more source

Rotorcraft research testing in the National Full-Scale Aerodynamics Complex at NASA Ames Research Center [PDF]

The unique capabilities of the National Full-Scale Aerodynamics Complex (NFAC) for testing rotorcraft systems are described. The test facilities include the 40- by 80-Foot Wind Tunnel, the 80- by 120-Foot Wind Tunnel, and the Outdoor Aerodynamic Research
Johnson, W., Smith, C. A., Warmbrodt, W.
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Laboratory testing of full scale lifeboat: pendulum tests

, 2010
A set of experiments were designed and conducted using a modified 20-person TEMPSC. The experiments involved suspending ice spheres from a line acting as a pendulum. Thesphere was then set at a specified angle, and allowed to freefall in the pendulum’s naturalarc until impact with the panel.
openaire   +2 more sources