Results 81 to 90 of about 11,216,273 (301)
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
This paper presents the response of a full-scale dry-stack masonry structure subject to earthquake loads. The following earthquakes were applied to the base of the structure: (a) North Ridge, (b) Llolleo, (c) El Centro and (d) Llolleo for the second time.
A Elvin, H C Uzoegbo
doaj
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Full scale pedestrian impact testing with PMHS: A pilot study [PDF]
The complexity of vehicle-pedestrian collisions necessitates extensive validation of pedestrian computational models. While body components can be individually simulated, overall validation of human pedestrian models requires full-scale testing with ...
Murphy, Dru +12 more
core
Hydrodynamic testing of a high performance skiff at model and full scale [PDF]
This study examines the hydrodynamic performance of a high performance skiff hull using three different physical testing techniques which may be used in early stage design for assessment of the upright resistance of sailing vessels.
Dai, S., Cameron, P., Day, A. H.
core +3 more sources
Two optical full-field strain measurement techniques, Digital Image Correlation and the Grid Method, are applied to characterise the strain-rate dependent constitutive behaviour of composite materials.
Longana, M.L.
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The development of high-speed railways is progressing at a very rapid pace worldwide. For example, in the UK, the construction of Phase 1 (225 km) of the HS2 line has now begun, and it will have a maximum operational speed of 360 km/h. In this paper, the
Woodward, Peter K. +20 more
core +1 more source

