Results 81 to 90 of about 11,216,273 (301)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Response of a full-scale dry-stack masonry structure subject to experimentally applied earthquake loading

open access: yesJournal of the South African Institution of Civil Engineers, 2011
This paper presents the response of a full-scale dry-stack masonry structure subject to earthquake loads. The following earthquakes were applied to the base of the structure: (a) North Ridge, (b) Llolleo, (c) El Centro and (d) Llolleo for the second time.
A Elvin, H C Uzoegbo
doaj  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Full scale pedestrian impact testing with PMHS: A pilot study [PDF]

open access: yes, 2004
The complexity of vehicle-pedestrian collisions necessitates extensive validation of pedestrian computational models. While body components can be individually simulated, overall validation of human pedestrian models requires full-scale testing with ...
Murphy, Dru   +12 more
core  

Hydrodynamic testing of a high performance skiff at model and full scale [PDF]

open access: yes, 2019
This study examines the hydrodynamic performance of a high performance skiff hull using three different physical testing techniques which may be used in early stage design for assessment of the upright resistance of sailing vessels.
Dai, S., Cameron, P., Day, A. H.
core   +3 more sources

Intermediate strain rate testing methodologies and full-field optical strain measurement techniques for composite materials characterisation

open access: yes, 2014
Two optical full-field strain measurement techniques, Digital Image Correlation and the Grid Method, are applied to characterise the strain-rate dependent constitutive behaviour of composite materials.
Longana, M.L.
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Geotechnical Centrifuge and Full-Scale Laboratory Testing for Performance Evaluation of Conventional and High-Speed Railway Track Structures

open access: yes, 2021
The development of high-speed railways is progressing at a very rapid pace worldwide. For example, in the UK, the construction of Phase 1 (225 km) of the HS2 line has now begun, and it will have a maximum operational speed of 360 km/h. In this paper, the
Woodward, Peter K.   +20 more
core   +1 more source

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