Results 111 to 120 of about 14,477,800 (285)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
N-1 Security-Constrained 8760-Hour Power Flow Generation Method for New-Type Power Systems
EnergiesThe high penetration of renewable energy introduces strong uncertainty into power system operating conditions, making it difficult for conventional planning methods to effectively satisfy N-1 security verification requirements.
Weigang Jin +7 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Systems and Soft ComputingWith the full advent of the digital age, user interface design is facing unprecedented challenges in terms of large-scale generation and personalized adaptation.
Fei Shen
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Managing the consistency of distributed documents [PDF]
, 2005 Many businesses produce documents as part of their daily activities: software engineers produce requirements specifications, design models, source code, build scripts and more; business analysts produce glossaries, use cases, organisation charts, and ...
Nentwich, C., Nentwich, Christian
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Contributions to the understanding of Bayesian consistency. [PDF]
Consistency of Bayesian nonparametric procedures has been the focus of a considerable amount of research. Here we deal with strong consistency for Bayesian density estimation. An awkward consequence of inconsistency is pointed out. We investigate reasons
Antonio Lijoi +2 more
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Derivation of an adjoint consistent discontinuous Galerkin discretization of the compressible Euler equations [PDF]
, 2006 Adjoint consistency - in addition to consistency - is the key requirement for discontinuous Galerkin (DG) discretizations to be of optimal order in L2 as well as measured in terms of target functionals.
Hartmann, Ralf
core