Results 131 to 140 of about 14,477,800 (285)

Use of the consistency check in the vector verification method

open access: yes, 1966
The consistency check is a type of frequency check in which full use is made of the space group symmetry. It is designed for application to a symmetry map, to a tentative atom map, to the results of superpositions, or to any pseudoelectron-density map ...
Mighell, Alan D.; Jacobson, R.A.
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Context dependence and consistency in dynamic choice under uncertainty: the case of anticipated regret [PDF]

open access: yes
We examine if and to what extent choice dispositions can allow dependence on contexts and maintain consistency over time, in a dynamic environment under uncertainty.
Takashi Hayashi
core  

Full scale data augmentation mining of power new energy eng-ineering based on multi-level grid of spatial information

open access: yesDianxin kexue
The current data of electric power new energy engineering presents complex characteristics of multi-source heterogeneity, spatiotemporal coupling, and spatial non stationarity, which make the boundaries of the full-scale data mining area fuzzy and lead ...
WANG Wei   +5 more
doaj  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Method Used to Test the Imaging Consistency of Binocular Camera's Left-right Optical System

open access: yes, 2016
fTo binocular camera, the consistency of optical parameters of the left and the right optical system is an important factor that will influence the overall imaging consistency.
Liu, Jie   +6 more
core   +1 more source

Full-scale data augmentation mining of electric power new energy engineering based on multi-level grid of spatial information

open access: yesDianxin kexue
The current data of electric power new energy engineering presents complex characteristics of multi-source heterogeneity, spatiotemporal coupling, and spatial non-stationarity, which make the boundaries of the full-scale data mining area fuzzy and lead ...
Wang Wei   +5 more
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

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