Two key binding events that collectively determine the catalytic efficiency of trans‐cleavage: (1) the substrate passing through the gap between the REC and NUC domains, determined by Kpass, and (2) the alignment of the substrate with the catalytic triad of the ribonucleoprotein, determined by Kalign.
Jianyu Hu +3 more
wiley +2 more sources
dsRADAR: Imaging and Detecting Cellular dsRNA by Repurposing RNA‐Binding Proteins
Double‐stranded RNA (dsRNA) plays an important role in the innate immune system, but can be misregulated in disease, leading to inflammation. Despite the importance of this motif, methods for detecting dsRNA remain limited. This work shows that ADAR3 can be repurposed to provide improved detection of dsRNA, which is demonstrated in the context of viral
Weina Cheng +7 more
wiley +2 more sources
Multiphase DNA–RNA artificial cells integrate a protective DNA shell, a transcriptionally active DNA core, and a functional RNA organelle. Spatial compartmentalization enables signal generation, external protein expression, and selective recapture via RNA aptamers. ABSTRACT Naturally occurring biomolecular condensates orchestrate key cellular processes
Maria Vonk‐de Roy +4 more
wiley +2 more sources
Aktivierung von Metallkomplexen durch Ultraschallwellen für eine gezielte Krebstherapie
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean +3 more
wiley +1 more source
An Improved Backoff Scheme and Its Performance Analysis for Full Duplex MAC Protocols in VLC Networks. [PDF]
Sawa Y, Sanada K, Hatano H, Mori K.
europepmc +1 more source
Full-duplex reflective beamsteering metasurface featuring magnetless nonreciprocal amplification. [PDF]
Taravati S, Eleftheriades GV.
europepmc +1 more source
Interference Management with Reflective In-Band Full-Duplex NOMA for Secure 6G Wireless Communication Systems. [PDF]
Khan R, Tsiga N, Asif R.
europepmc +1 more source
Nonlinear Digital Self-Interference Cancellation in In-Band Full-Duplex Systems with Complex-Valued Temporal Convolution. [PDF]
Chen J, Wang X, Wang R, Zhao H.
europepmc +1 more source
The Optimal Power Allocation for Sum Rate and Energy Efficiency of Full-Duplex Two-Way Communication Network. [PDF]
Ye H, Chen Z, Jia Y, Chen S.
europepmc +1 more source
Cooperative Design of Ranging and Communication for In-Band Full-Duplex Inter-Satellite Links. [PDF]
Feng H +7 more
europepmc +1 more source

