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Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

open access: yesAdvanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham   +8 more
wiley   +1 more source

Three-Mode Opportunistic Full-Duplex Switching

open access: yesIEEE Access
This paper proposes a novel opportunistic full-duplex (FD) scheme switching among three duplex modes (DMs) of half duplex (HD), three node FD (TNFD) and bidirectional FD (BiFD) for the cellular systems.
Hyungseop Son, Kwonhue Choi
doaj   +1 more source

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