Patient-reported outcomes and qualitative interviews in patients with estrogen receptor-positive/human epidermal growth factor receptor 2-negative advanced breast cancer: results from the phase III EMBER-3 trial. [PDF]
Curigliano G +23 more
europepmc +1 more source
<i>ESR1</i>-Guided Endocrine Switching in HR-Positive Metastatic Breast Cancer: From Detection to Risk-Adapted Decision in SERENA-6. [PDF]
Abusanad A.
europepmc +1 more source
Endocrine therapy reprogramming of breast cancer facilitates metastatic escape via upregulation of P-Rex1/Rac1 signalling. [PDF]
Fernandez KJ +34 more
europepmc +1 more source
Sequential CDK4/6 inhibition in bone-only metastatic HR+/HER2- breast cancer: a case of prolonged disease control with abemaciclib after clinical progression on palbociclib-based therapy. [PDF]
Peng X, Chang W.
europepmc +1 more source
WITHDRAWN: From CDK4/6 to CDK2 and KAT: Evolving therapeutic approaches in HR+/HER2- breast cancer.
Stachyra P +4 more
europepmc +1 more source
Fulvestrant: pharmacokinetics and pharmacology
Fulvestrant is a new type of oestrogen receptor (ER) antagonist with no agonist activity and a novel pharmacological profile. Fulvestrant has been shown to significantly reduce cellular levels of the ER and progesterone receptor in both preclinical ...
J F R Robertson
exaly +2 more sources
Fulvestrant (‘Faslodex’): Current and future role in breast cancer management
Fulvestrant ('Faslodex') is a new type of estrogen receptor antagonist with no agonist effects, that reduces cellular levels of both estrogen and progesterone receptors.
Anthony Howell
exaly +2 more sources
MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways [PDF]
Fulvestrant is a selective estrogen receptor downregulator (SERD) and highly effective antagonist to hormone-sensitive breast cancers following failure of previous tamoxifen or aromatase inhibitor therapies.
Kenneth P Nephew, X Rao
exaly +2 more sources

