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Fulvestrant treatment alters MDM2 protein turnover and sensitivity of human breast carcinoma cells to chemotherapeutic drugs [PDF]
Cancer Letters, 2014 The human homologue of mouse double minute 2 (MDM2) is overexpressed in tumors and contributes to tumorigenesis through inhibition of p53 activity. We investigated the effect of the anti-estrogen fulvestrant on MDM2 expression and sensitivity of estrogen
Jin-Ming Yang +2 more
exaly +2 more sources
European Journal of Cancer, 2007 Fulvestrant (Faslodex™) reduces markers of hormone sensitivity and proliferation in postmenopausal women. This Phase II double-blind, randomised, multicentre study compared the effects of a single 250mg intramuscular dose of fulvestrant and placebo 14–21
Julia Gee +2 more
exaly +2 more sources
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Fulvestrant for advanced breast cancer: A meta-analysis
Cancer Treatment Reviews, 2013Boštjan Šeruga +2 more
exaly
Fulvestrant versus anastrozole for the treatment of advanced breast carcinoma
Cancer, 2005John Robertson +2 more
exaly
Activity of fulvestrant in HER2-overexpressing advanced breast cancer
Annals of Oncology, 2010Patrick Neven +2 more
exaly