Results 1 to 10 of about 1,588 (136)

Fumagillin Shortage: How to Treat Enterocytozoon bieneusi Microsporidiosis in Solid Organ Transplant Recipients in 2024? [PDF]

open access: yesTransplant International
Intestinal microsporidiosis caused by Enterocytozoon bieneusi is an opportunistic infection that especially affects solid organ transplant (SOT) recipients.
Cyril Garrouste   +59 more
doaj   +2 more sources

Fumagillin regulates stemness and malignancies in cancer stem-like cells derived from liver cancer via targeting to MetAP-2.

open access: yesPLoS ONE, 2023
BackgroundCancer relapse is associated with the presence of cancer stem-like cells (CSCs), which lead to multidirectional differentiation and unrestricted proliferative replication.
Ke Zhang, Jian Hu, Ziyi Zhao
doaj   +2 more sources

Establishment and application of a loop-mediated isothermal amplification method based on MetAP2 gene for the detection of Nosema bombycis in silkworms (Bombyx mori) [PDF]

open access: yesFrontiers in Veterinary Science
Pebrine, caused by Nosema bombycis, is a devastating disease of silkworms that causes huge economic losses to the sericulture farmers. Although pebrine is a quarantine disease, currently the development of effective molecular diagnostic or therapeutic ...
Izhar Hyder Qazi   +6 more
doaj   +2 more sources

Fall Treatment with Fumagillin Contributes to an Overwinter Shift in Vairimorpha Species Prevalence in Honey Bee Colonies in Western Canada [PDF]

open access: yesLife
(1) Background: Microsporidiosis (nosemosis) is an intestinal disorder of adult honey bees caused by the microsporidian pathogens Vairimorpha apis and Vairimorpha ceranae.
Sarah Biganski   +11 more
doaj   +2 more sources

A Systematic Review of Fumagillin Field Trials for the Treatment of Nosema Disease in Honeybee Colonies [PDF]

open access: yesInsects
This article systematically reviews controlled field trials of fumagillin dicyclohexylamine in honeybee colonies to determine whether fumagillin effectively controls nosema and whether it is beneficial to colonies.
Michael Peirson, Stephen F. Pernal
doaj   +2 more sources

The effects of protein supplementation, fumagillin treatment, and colony management on the productivity and long-term survival of honey bee (Apis mellifera) colonies. [PDF]

open access: yesPLoS ONE
In this study, we intensively measured the longitudinal productivity and survival of 362 commercially managed honey bee colonies in Canada, over a two-year period. A full factorial experimental design was used, whereby two treatments were repeated across
Michael Peirson   +6 more
doaj   +2 more sources

Vairimorpha (Nosema) ceranae can promote Serratia development in honeybee gut: an underrated threat for bees? [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology
The genus Serratia harbors opportunistic pathogenic species, among which Serratia marcescens is pathogenic for honeybees although little studied. Recently, virulent strains of S.
Chiara Braglia   +11 more
doaj   +2 more sources

Identification of new drug candidates against Trichomonas gallinae using high-throughput screening [PDF]

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2023
Trichomonas gallinae is a protozoan parasite that is the causative agent of trichomoniasis, and infects captive and wild bird species throughout the world.
Shengfan Jing   +8 more
doaj   +2 more sources

MetAP2 as a Therapeutic Target for Obesity and Type 2 Diabetes: Structural Insights, Mechanistic Roles, and Inhibitor Development [PDF]

open access: yesBiomolecules
Type 2 Diabetes Mellitus (T2DM) and obesity are globally prevalent metabolic disorders characterized by insulin resistance, impaired glucose metabolism, and excessive adiposity.
Dong Oh Moon
doaj   +2 more sources

Exploring Eco-Friendly Microbial Strategies for Nosemosis Control in Honeybee [PDF]

open access: yesMicroorganisms
Nosemosis is an intestinal infection caused by intracellular fungal organisms from the Vairimorpha (formerly Nosema) group, which seriously harms honeybee colonies and is a factor in their worldwide decline.
Bogdan Tache   +3 more
doaj   +2 more sources

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