Results 41 to 50 of about 2,350 (205)

Anti-angiogenic drug loaded liposomes: Nanotherapy for early atherosclerotic lesions in mice. [PDF]

open access: yesPLoS ONE, 2018
Fumagillin-loaded liposomes were injected into ApoE-KO mice. The animals were divided into several groups to test the efficacy of this anti-angiogenic drug for early treatment of atherosclerotic lesions.
Isabel Pont   +7 more
doaj   +1 more source

Identification of new drug candidates against Trichomonas gallinae using high-throughput screening

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2023
Trichomonas gallinae is a protozoan parasite that is the causative agent of trichomoniasis, and infects captive and wild bird species throughout the world.
Shengfan Jing   +8 more
doaj   +1 more source

Fumagillin affects malignant behaviors in CSCs.

open access: yes, 2023
A. After Fumagillin treatment, cell viability of Huh-7 or SNU-449 CSCs from day 1–5 was measured by performing CCK-8 assay ...
Ziyi Zhao (8139873)   +2 more
core   +1 more source

Local inhibition of angiogenesis results in an atrophic non-union in a rat osteotomy model [PDF]

open access: yesEuropean Cells & Materials, 2011
Long bone and in particular tibia fractures frequently fail to heal. A disturbed revascularisation is supposed to be a major cause for impaired bone healing or the development of non-unions.
M Fassbender   +5 more
doaj  

Mathematical modelling of population and food storage dynamics in a honey bee colony infected with Nosema ceranae

open access: yesHeliyon, 2020
Unusually high wintering losses of Apis mellifera in recent years has raised concerns regarding the well-being and productivity of honey bees across the globe.
J. Reilly Comper, Hermann J. Eberl
doaj   +1 more source

Recent Advances in the Biocontrol of Nosemosis in Honey Bees (Apis mellifera L.)

open access: yesJournal of Fungi, 2022
Nosemosis is a disease triggered by the single-celled spore-forming fungi Nosema apis and Nosema ceranae, which can cause extensive colony losses in honey bees (Apis mellifera L.). Fumagillin is an effective antibiotic treatment to control nosemosis, but
Massimo Iorizzo   +7 more
doaj   +1 more source

Fumarranol, a Rearranged Fumagillin Analogue That Inhibits Angiogenesis in Vivo

open access: yes, 2016
The fumagillin family of natural products inhibits angiogenesis through the irreversible inhibition of the type 2 methionine aminopeptidase (MetAP2). Herein is reported a novel fumagillin analogue named fumarranol.
Curtis R. Chong (269141)   +3 more
core   +1 more source

Volatile Organic Compounds Emitted by Fungi Have Substantial Effects on Growth and Disease Resistance in Arabidopsis thaliana

open access: yesPlant, Cell &Environment, Volume 49, Issue 9, Page 7168-7190, September 2026.
ABSTRACT Volatile organic compounds (VOCs) emitted by certain fungi have previously been suggested to modulate plant development and their response to stresses. While some fungal species, such as Trichoderma harzianum, are known to produce VOCs, the production of VOCs in other phylogenetically divergent species, such as Mucor mucedo, was previously ...
Sara Yugueros   +7 more
wiley   +1 more source

Orchestrated Biosynthesis of the Secondary Metabolite Cocktails Enables the Producing Fungus to Combat Diverse Bacteria

open access: yesmBio, 2022
Fungal secondary metabolites with antibiotic activities can promote fungal adaptation to diverse environments. Besides the global regulator, individual biosynthetic gene clusters (BGCs) usually contain a pathway-specific transcription factor for the ...
Yanlei Sun   +4 more
doaj   +1 more source

Identification of Novel Therapeutic Agent Candidates Through High Throughput Screening With Chemical Library Based on Molecular Subclassification in Canine Histiocytic Sarcoma Cell Lines

open access: yesVeterinary and Comparative Oncology, Volume 24, Issue 3, Page 554-567, September 2026.
ABSTRACT Effective chemotherapy for canine histiocytic sarcoma (CHS) has yet to be established. In our previous study, CHS cell lines were subclassified into two groups based on their gene expression profiles: Group A and Group B. This study aimed to identify novel therapeutic agents that are effective against each CHS subgroup, and we performed high ...
Hiroki Sakuma   +6 more
wiley   +1 more source

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