Results 51 to 60 of about 2,350 (205)

Consequences of phenological shifts are determined by the number of generations per season

open access: yesEcology, Volume 107, Issue 7, July 2026.
Abstract The order and timing of species' arrival in a community can often change species interactions. Termed priority effects, this phenomenon arises in communities with drastically different life histories (e.g., bacteria, insects, and amphibians), yet how their life history traits affect the consequences of priority effects in seasonal systems ...
Heng‐Xing Zou, Volker H. W. Rudolf
wiley   +1 more source

Identification of candidate agents active against N. ceranae infection in honey bees: establishment of a medium throughput screening assay based on N. ceranae infected cultured cells. [PDF]

open access: yesPLoS ONE, 2015
Many flowering plants in both natural ecosytems and agriculture are dependent on insect pollination for fruit set and seed production. Managed honey bees (Apis mellifera) and wild bees are key pollinators providing this indispensable eco- and agrosystem ...
Sebastian Gisder, Elke Genersch
doaj   +1 more source

Extracts From Grapefruit (Citrus paradisi) Peel via Microwave‐Assisted and Conventional Extractions: Evaluation of Nosema Infection and Toxicity in Honey Bees

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Conventional and microwave‐assisted extractions of grapefruit peels were optimized using response surface methodology (RSM) based on TPC, TFC, and antioxidant activity (DPPH). The phytochemical profiles of the two optimum extracts were characterized via HPLC before evaluating their acute and chronic toxicity, as well as their effects on honey bee (Apis
Muhammet Mükerrem Kaya   +4 more
wiley   +1 more source

Treatment with fumagillin is not associated with differences in capillary density in MCT-injured animals.

open access: yes, 2012
Rats were injected with MCT and treated with fumagillin or vehicle control beginning at 14 d after MCT injury as described in Materials and Methods.
Revathi Rajkumar (173127)   +10 more
core   +1 more source

Proteasome Inhibition Is an Effective Treatment Strategy for Microsporidia Infection in Honey Bees

open access: yesBiomolecules, 2021
The microsporidia Nosema ceranae is an obligate intracellular parasite that causes honey bee mortality and contributes to colony collapse. Fumagillin is presently the only pharmacological control for N. ceranae infections in honey bees.
Emily M. Huntsman   +5 more
doaj   +1 more source

Prodrug Strategies in Atherosclerosis: Targeted Delivery and Therapeutic Advances

open access: yesCardiovascular Therapeutics, Volume 2026, Issue 1, 2026.
Atherosclerosis is an advancing and complex vascular condition primarily associated with sustained inflammatory responses, oxidative imbalance, and disruptions in lipid homeostasis. These pathological features render it a major contributor to the global burden of cardiovascular disease, encompassing both morbidity and mortality.
Elaheh Mirhadi   +4 more
wiley   +1 more source

Inhibition of neutrophil function following exposure to the Aspergillus fumigatus toxin fumagillin [PDF]

open access: yes, 2010
The filamentous fungus Aspergillus fumigatus produces a variety of enzymes and toxins that may facilitate fungal colonization of tissue and evasion of the host immune response. One such toxin, fumagillin, was investigated for its ability to inhibit the
Fallon, John P.   +2 more
core   +1 more source

A MetAP2 inhibitor blocks adipogenesis, yet improves glucose uptake in cells

open access: yesAdipocyte, 2019
Adipose tissue expansion involves angiogenesis to remodel its capillary network. The enzymemethionine aminopeptidase 2(MetAP2) promotes angiogenesis.MetAP2 inhibitors suppress angiogenesis and have potential anti-obesity effect.
Md Abu Bakkar Siddik   +4 more
doaj   +1 more source

Natural Substances, Probiotics, and Synthetic Agents in the Treatment and Prevention of Honeybee Nosemosis

open access: yesPathogens, 2022
Honeybees are important pollinators, but they are continuously exposed to a variety of fungal and bacterial diseases. One of the various diseases affecting honeybees is nosemosis caused by microsporidia from the Nosema genus.
Magdalena Kunat-Budzyńska   +6 more
doaj   +1 more source

Immune priming of honey bees protects against a major microsporidian pathogen

open access: yesPest Management Science, Volume 81, Issue 12, Page 7939-7949, December 2025.
We immune‐primed honey bees at two developmental stages in the laboratory and the field with heat‐killed Nosema ceranae spores. When subsequently fed live spores, immune‐primed adults had lower infection levels. Abstract BACKGROUND Honey bees face significant threats from pathogens like Nosema ceranae, a microsporidian parasite that contributes to ...
James C. Nieh   +6 more
wiley   +1 more source

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