Fumagillin regulates stemness and malignancies in cancer stem-like cells derived from liver cancer via targeting to MetAP-2. [PDF]
PLoS ONE, 2023 BackgroundCancer relapse is associated with the presence of cancer stem-like cells (CSCs), which lead to multidirectional differentiation and unrestricted proliferative replication.
Ke Zhang, Jian Hu, Ziyi Zhao
doaj +2 more sources
Nosema ceranae escapes fumagillin control in honey bees.
PLoS Pathogens, 2013 Fumagillin is the only antibiotic approved for control of nosema disease in honey bees and has been extensively used in United States apiculture for more than 50 years for control of Nosema apis.
Wei-Fone Huang +3 more
doaj +2 more sources
Aspergillus fumigatus Fumagillin Contributes to Host Cell Damage [PDF]
Journal of Fungi, 2021 The activity of fumagillin, a mycotoxin produced by Aspergillus fumigatus, has not been studied in depth. In this study, we used a commercial fumagillin on cultures of two cell types (A549 pneumocytes and RAW 264.7 macrophages).
Xabier Guruceaga +12 more
doaj +2 more sources
Enhanced Fumagillin Production by Optimizing Fermentation and Purification Techniques
FermentationFumagillin is a complex biomolecule. Nowadays, the separation and purification techniques of fumagillin still need to be optimized. In this study, the yield of fumagillin was examined in relation to temperature, pH, inoculation volume, rotation speed ...
Zili Feng +5 more
doaj +2 more sources
Enterocytozoon bieneusi Microsporidiosis in Stem Cell Transplant Recipients Treated with Fumagillin
Emerging Infectious Diseases, 2017 Enterocytozoon bieneusi microsporidiosis is an emerging disease in immunocompromised patients. We report 2 cases of this disease in allogeneic hematopoietic stem cell transplant patients successfully treated with fumagillin. Thrombocytopenia occurred but
Iryna Bukreyeva +9 more
doaj +2 more sources
Fumagillin-induced chromosome aberrations in mouse bone-marrow cells [PDF]
Archives of Biological Sciences, 2010 The genotoxicity of fumagillin was evaluated assessing the mitotic index and chromosome aberrations in mouse bone-marrow cells. Mice were given fumagillin orally in doses 5, 10 and 20 mg/kg bw.
Stanimirović Z. +3 more
doaj +2 more sources
Fumagillin and Dicyclohexylamine in Apiculture [PDF]
, 2015 Nosema disease of the Western honey bee (Apis mellifera L.), is caused by two distinct microsporidian fungal species, Nosema ceranae Fries et al. and Nosema apis Zander. N. apis infection of A. mellifera was first documented in 1909, while N. ceranae infection of A. mellifera was described in 1996. N.
van den Heever, Johan P
openaire +2 more sources
Cytogenetic Effects of Honey Contaminated With Fumagillin (Dicyclohexylamine) on Male Mice Mus Musculus Balb/C In Vivo [PDF]
Science Journal of University of Zakho, 2013 Cytogenetic effects of honey contaminated with fumagillin that collected from different sources in Duhok province was investigated in mouse bone-marrow cells using damaged cells%, (chromatids and chromosomal aberrations and mitotic index (M.I).
Soleen Sardar Zuhdi +1 more
doaj +1 more source
Microsporidium Keratitis After Hurricane Francine: A Case Report. [PDF]
Case Rep Ophthalmol MedMicrosporidial ocular infections are being increasingly reported, especially in temperate climates. In this case report, we describe five patients who presented to a private ophthalmology practice in Southeastern Louisiana in 2024, all within 3 months of Hurricane Francine landing.
Dwyer ZA, Lau SV.
europepmc +2 more sources
Cytogenetic Effects Of Fumagillin On Male Mice (Mus musculus)
Tikrit Journal of Pure Science, 2023 The cytogenetic effects of Fumagillin were evaluated according to Mitotic Index (M.I) and aberration of metaphase chromosomes in bone marrow cells(CA) of white mice. The fumagillin was given as repeated oral gavages for 7 successive days after preparing
Wajdi Sabeeh Sadeq +2 more
doaj +1 more source