ανβ3-targeted copper nanoparticles incorporating an Sn 2 lipase-labile fumagillin prodrug for photoacoustic neovascular imaging and treatment [PDF]
licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.
Allen, John S +7 more
core +2 more sources
What proteomics has taught us about honey bee (Apis mellifera) health and disease
Abstract The Western honey bee, Apis mellifera, is currently navigating a gauntlet of environmental pressures, including the persistent threat of parasites, pathogens, and climate change – all of which compromise the vitality of honey bee colonies.
Maor Arad +6 more
wiley +1 more source
The dicyclohexylamine salt of fumagillin is currently used in some countries to control nosema disease in honey bee colonies. Chemical residues in honey resulting from the use of chemotherapies in apiculture are a food safety concern.
Thomas S. Thompson +2 more
doaj +1 more source
Microsporidia Vairimorpha (Nosema) ceranae is an emergent parasite of honeybee Apis mellifera and has a great concern to apiculture due to high pathogenesity and fumagillin resistance.
Senderskiy Igor +2 more
doaj +1 more source
Cellular trafficking of Sn-2 phosphatidylcholine prodrugs studied with fluorescence lifetime imaging and super-resolution microscopy [PDF]
While ...
Achilefu, Samuel +9 more
core +1 more source
Drug‐phospholipid conjugate nano‐assembly for drug delivery
Drug‐phospholipid conjugates (DPCs) possess the prodrug characteristics and self‐assembly abilities, making them a potential alternative to traditional phospholipids in the preparation of nanomedicines. The nano‐assemblies formed by DPCs exhibit decent advantages such as high drug‐loading capacity and strong stability, showing great translational ...
Ding Zhao +6 more
wiley +1 more source
Heterologous Expression and Purification of \u3cem\u3eVibrio proteolyticus (Aeromonas proteolytica)\u3c/em\u3e Aminopeptidase: A Rapid Protocol [PDF]
Metalloaminopeptidases (mAPs) are enzymes that are involved in HIV infectivity, tumor growth and metastasis, angiogenesis, and bacterial infection. Investigation of structure–function relationships in mAPs is a prerequisite to rational design of anti-mAP
Bennett, Brian, Hartley, Mariam
core +1 more source
Anti-angiogenesis therapy in the Vx2 rabbit cancer model with a lipase-cleavable Sn 2 taxane phospholipid prodrug using αvβ3-targeted theranostic nanoparticles [PDF]
In nanomedicine, the hydrophobic nature of paclitaxel has favored its incorporation into many nanoparticle formulations for anti-cancer chemotherapy. At lower doses taxanes are reported to elicit anti-angiogenic responses.
Allen, John S +13 more
core +2 more sources
Interactions between microsporidia and other members of the microbiome
Abstract The microbiome is the collection of microbes that are associated with a host. Microsporidia are intracellular eukaryotic parasites that can infect most types of animals. In the last decade, there has been much progress to define the relationship between microsporidia and the microbiome.
Jonathan Tersigni +3 more
wiley +1 more source
Advances in Atherosclerosis Theranostics Harnessing Iron Oxide‐Based Nanoparticles
This review mainly focuses on the advances and prospects in the iron oxide nanoparticles‐based atherosclerosis theranostics, which may simultaneously possess targeting, diagnostic, and therapeutic functions. A comprehensive and detailed summary of related researches are provided according to three therapeutic strategies, encompassing the chemical ...
Shi Wang +4 more
wiley +1 more source

