Impact of disease-modifying therapies on pregnancy outcomes in multiple sclerosis: a prospective cohort study from the German multiple sclerosis and pregnancy registry. [PDF]
Lancet Reg Health EurBast N +8 more
europepmc +1 more source
The FASEB Journal, Volume 40, Issue 7, 15 April 2026.We investigated the roles of PKM2, PKM1, and LDHA in retinal metabolism and structural integrity. In the normal retina, these enzymes are maintained at defined levels that support photoreceptor function. Rod‐specific deletion of LDHA, alone or with PKM2, caused age‐dependent degeneration, as PKM1 induction did not reach levels comparable to PKM2.
Ammaji Rajala +3 more
wiley +1 more source
British Journal of Clinical Pharmacology, Volume 92, Issue 4, Page 1109-1116, April 2026.Aims To translate a PBPK model developed for the direct oral anticoagulant, dabigatran etexilate, the prodrug of dabigatran, based on data obtained from healthy men to healthy non‐pregnant, pregnant and post‐partum women. To evaluate safety and efficacy of dabigatran etexilate in post‐partum women using simulations and design a future clinical study to
Kayode Ogungbenro +3 more
wiley +1 more source
Diroximel Fumarate-Loaded Solid Lipid Nanoparticles (DRF-SLNs) as Potential Carriers for the Treatment of Multiple Sclerosis: Preformulation Study. [PDF]
Int J Mol SciSantonocito D +7 more
europepmc +1 more source
Brain and Behavior, Volume 16, Issue 4, April 2026.This study systematically examined circulating and cerebrospinal fluid metabolites in relation to malignant brain neoplasms. Leveraging large‐scale population‐based genome‐wide association data, the integrated analysis identified metabolites and metabolic pathways potentially linked to brain malignancy, providing supportive evidence for biomarker ...
Xinyin Zhang +5 more
wiley +1 more source
Neuroprotective and Anti-Inflammatory Effects of Dimethyl Fumarate, Monomethyl Fumarate, and Cannabidiol in Neurons and Microglia. [PDF]
Int J Mol SciSánchez-Sanz A +4 more
europepmc +1 more source
New perspectives for step-growth polymerization : light driven step-growth fused with chain extension via RAFT polymerization [PDF]
, 2017 Barner-Kowollik, Christopher +6 more
core +1 more source
Cancer Innovation, Volume 5, Issue 2, April 2026.Chimeric antigen receptor (CAR) T‐cell therapy, although revolutionary for haematological malignancies, faces significant challenges, including T‐cell exhaustion, limited persistence, and treatment‐related toxicity. The integration of small‐molecule compounds offers a promising strategy to overcome these limitations.
Rangzi Yi +3 more
wiley +1 more source
Dimethyl Fumarate Treatment for Psoriasis in Real-World Clinical Practice: An Analysis from the Swiss Registry. [PDF]
DermatologyMaul LV +13 more
europepmc +1 more source
Advancement in Anaerobic Digestion for Scaling‐Up Biogas Production Through Food Waste Valorization
ChemBioEng Reviews, Volume 13, Issue 2, April 2026.The review article begins with an introduction that covers the overview, food waste (FW) classification, and the steps involved in producing biogas through anaerobic digestion (AD). Following that, it describes the process for producing biogas, including single‐, two‐, and multistage systems, mesophilic and thermophilic digestion, and wet and dry ...
Poulami Chatterjee +2 more
wiley +1 more source