Results 161 to 170 of about 2,275 (253)

Targeted activation of Nrf2 at sites of oxidative stress reverses doxorubicin-induced cognitive impairments in mice. [PDF]

Brain Behav Immun
Singh AK, Ruiz D, Pandey VK, Ur Rasheed MS, Turner DJL, Avery TD, Abell AD, Grace PM.   +7 more
europepmc   +1 more source

Transgenic selection and underlying mechanisms in apicomplexan parasites

The FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju, Rakhee Lohia, Nishith Gupta   +2 more
wiley   +1 more source

Impact of disease-modifying therapies on pregnancy outcomes in multiple sclerosis: a prospective cohort study from the German multiple sclerosis and pregnancy registry. [PDF]

Lancet Reg Health Eur
Bast N, Dost-Kovalsky K, Haben S, Friedmann N, Witt L, Oganowski T, Gold R, Thiel S, Hellwig K.   +8 more
europepmc   +1 more source

The epigenetic landscape of skeletal muscle in response to exercise and aging

The FEBS Journal, EarlyView.
Epigenetic mechanisms regulate gene expression in response to exercise and aging, thereby supporting skeletal muscle plasticity. Acute exercise induces chromatin remodeling through histone modifications and DNA methylation, promoting the expression of exercise‐responsive genes.
Sabrina Champsi, David A. Hood
wiley   +1 more source

Treatment Options for the Comorbidity of Multiple Sclerosis with Other Chronic Inflammatory Diseases. [PDF]

Dtsch Arztebl Int
Bittner S, Kriegel MA, Siegmund B, Kümpfel T, Sabat R.   +4 more
europepmc   +1 more source

Common pathways and outliers in glucose catabolism across Trypanosomatidae

The FEBS Journal, EarlyView.
Trypanosomatid parasites, including Trypanosoma sp., Leishmania sp., Phytomonas sp., and Vickermania sp., share a common motif: a metabolism built around the glycosome, a unique peroxisome‐derived organelle housing the first steps of glycolysis. Yet, these organisms have evolved remarkably diverse strategies to catabolize glucose, excreting distinct ...
Fred R. Opperdoes, Mayke B. Alencar, Ariel M. Silber, Ingrid Škodová‐Sveráková, Kristína Záhonová, Vyacheslav Yurchenko   +5 more
wiley   +1 more source

Comparative Effectiveness of Diroximel Fumarate vs. Dimethyl Fumarate in Persons with Multiple Sclerosis: A US Claims Analysis of Relapse Outcomes. [PDF]

Adv Ther
Bandari D, Conway D, Dong L, Hong N, Li M, Littlewood A, Roy M, Ulin S, Zou C, Amerian-Williams B, Belviso N, Lewin JB, Mendoza JP, Avila M.   +13 more
europepmc   +1 more source

Hepatitis B Virus Infection Status in Japanese Children Prior to Universal Vaccination: Sustained Effectiveness of Mother‐to‐Child Transmission Prevention and Residual Infection Burden

Hepatology Research, EarlyView.
ABSTRACT Aim To evaluate the effectiveness of prevention of mother‐to‐child transmission (PMTCT) over 25 years, we conducted a nationwide epidemiological survey through a comprehensive assessment of hepatitis B virus (HBV) markers. Methods Two cohorts were recruited before universal vaccination: children aged 9–10 years undergoing school health ...
Aiko Sakai, Yasuhito Tanaka, Hiroshi Yotsuyanagi, Masaya Sugiyama, Ichiro Morioka, Kiyotaka Kosugiyama, Kimiaki Uetake, Tomohiro Katsuta, Atsushi Imamura, Tomoko Takano, Hitoshi Tajiri, Akihito Ishida, Kosuke Ushijima, Yumiko Nakashima, Hiroyuki Moriuchi, Shinji Iwane, Kota Sawada, Yosuke Shimizu, Yukari Uemura, Manabu Tagawa, Masashi Mizokami, Ryo Sumazaki   +21 more
wiley   +1 more source

Neuroprotective and Anti-Inflammatory Effects of Dimethyl Fumarate, Monomethyl Fumarate, and Cannabidiol in Neurons and Microglia. [PDF]

Int J Mol Sci
Sánchez-Sanz A, Coronado-Albi MJ, Muñoz-Viana R, García-Merino A, Sánchez-López AJ.   +4 more
europepmc   +1 more source

Dietary counselling and exercise training for lipid management in people living with HIV: A systematic review and meta‐analysis

HIV Medicine, EarlyView.
Abstract Objectives Dyslipidaemia is highly prevalent among people living with human immunodeficiency virus (HIV) and contributes to increased cardiovascular risk. Although lifestyle interventions are recommended, evidence specific to people living with HIV remains limited. Previous reviews have primarily focused on dietary interventions or low‐density
Maki Aomori, Hitomi Maeda
wiley   +1 more source