Results 131 to 140 of about 5,939,728 (334)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Fitted Value Function Iteration With Probability One Contractions [PDF]

This paper studies a value function iteration algorithm that can be applied to almost all stationary dynamic programming problems. Using nonexpansive function approximation and Monte Carlo integration, we develop a randomized fitted Bellman operator and ...
Jenö Pál, John Stachurski
core  

Comparative Study of Regression Models for Continuous Function Approximation

Information
Regression models are widely used for continuous function approximation in applied research, yet selecting an appropriate model remains challenging for applied users who must balance predictive accuracy, interpretability, robustness, computational cost ...
Tamás Storcz, Gábor Gyurák, Zsolt Ercsey   +2 more
doaj   +1 more source

Blade Rub-Impact Fault Identification Using Autoencoder-Based Nonlinear Function Approximation and a Deep Neural Network. [PDF]

Sensors (Basel), 2020
Prosvirin AE, Piltan F, Kim JM.
europepmc   +1 more source

A Chebyshev Method for Matrix Function Approximation [PDF]

Daniel Eckhardt, Volker Grimm, Marlis Hochbruck   +2 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Identification of mechanical parameters of fiber-reinforced composites by frequency response function approximation method. [PDF]

Sci Prog, 2020
Li H, Xue P, Rong W, Li X, Wen B.
europepmc   +1 more source

ON APPROXIMATELY SUBADDITIVE FUNCTIONS

Demonstratio Mathematica, 1990
Let (X,+) be a commutative, 2-divisible group. Then ever; approximately subadditive functional (i.e. f» X —• IR, R denotes the real line, such that f(x+y)^ f(x)+f(y)+ £ for some £>0 and all x,yeX), is minorized by a Jensen functional. Moreover, if fs X— R is approximately convex (in the sense of Jensen) function, then there exists convex (in the sense ...
openaire   +3 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source