Results 111 to 120 of about 373,199 (312)
A Neural Network Approximation Based on a Parametric Sigmoidal Function
Mathematics, 2019 It is well known that feed-forward neural networks can be used for approximation to functions based on an appropriate activation function. In this paper, employing a new sigmoidal function with a parameter for an activation function, we consider a ...
Beong In Yun
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Approximations of functions on the integers [PDF]
Pacific Journal of Mathematics, 1963 Rose, Gene F., Ullian, Joseph S.
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Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Sequential Optimal Recovery: A Paradigm for Active Learning
, 1995 In most classical frameworks for learning from examples, it is assumed that examples are randomly drawn and presented to the learner. In this paper, we consider the possibility of a more active learner who is allowed to choose his/her own examples ...
Partha Niyogi, Niyogi, Partha
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
АППРОКСИМАЦИЯ СИЛЫ СОПРОТИВЛЕНИЯ ВОЗДУХА ДВИЖЕНИЮ СНАРЯДОВ АНАЛИТИЧЕСКИМИ ФУНКЦИЯМИ
Sučasnì Informacìjnì Tehnologìï u Sferì Bezpeki ta Oboroni, 2015 В статтье проводится выбор и обоснование аналитических функций, которые используются для описания силы сопротивления воздуха. Рассматриваются характерные участки и особенности изменения функций сопротивления воздуха в зависимосты от скорости полета ...
Volodymir I. Grabchac +2 more
doaj
On the Bounds of Function Approximations [PDF]
, 2019 Accepted as a full paper at ICANN 2019.
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source