Results 141 to 150 of about 373,199 (312)
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
IEEE AccessReinforcement Learning is a branch of machine learning to learn control strategies that achieve a given objective through trial-and-error in the environment.
Yuuya Watabe, Takeshi Shibuya
doaj +1 more source
Best Approximation Of Bounded Functions By Continuous Functions
, 2015 [No abstract available]412135148Amir, Chebyshev centers and uniform convexity (1978) Pacific Journal of Mathematics, 77, pp. 1-6Amir, Deutsch, Approximation by certain subspaces in the Banach space of continuous vector-valued functions (1979) J.
Roversi M.S.M., ROVERSI, MSM
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Approximation of Jump Diffusions in Finance and Economics [PDF]
In finance and economics the key dynamics are often specified via stochastic differential equations (SDEs) of jump-diffusion type. The class of jump-diffusion SDEs that admits explicit solutions is rather limited.
Nicola Bruti-Liberati, Eckhard Platen
core
ON APPROXIMATELY SUBADDITIVE FUNCTIONS
Demonstratio Mathematica, 1990 Let (X,+) be a commutative, 2-divisible group. Then ever; approximately subadditive functional (i.e. f» X —• IR, R denotes the real line, such that f(x+y)^ f(x)+f(y)+ £ for some £>0 and all x,yeX), is minorized by a Jensen functional. Moreover, if fs X— R is approximately convex (in the sense of Jensen) function, then there exists convex (in the sense ...
openaire +3 more sources
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Recursive Approximation of the High Dimensional max Function
An alternative smoothing method for the high dimensional max functionhas been studied. The proposed method is a recursive extension of thetwo dimensional smoothing functions.
Zhang, S. +3 more
core
Controlling complexity of RBF networks by similarity
, 2007 Rückert U, Eickhoff R. Controlling complexity of RBF networks by similarity. In: ESANN. 2007: 181-186.Using radial basis function networks for function approximation tasks suffers from unavailable knowledge about an adequate network size.
Eickhoff, Ralf, Rückert, Ulrich
core
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source