Results 71 to 80 of about 302,091 (291)

Learning Infinite-horizon Average-reward MDPs with Linear Function\n Approximation [PDF]

open access: green, 2020
Chen-Yu Wei   +3 more
openalex   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

An Approximate Consumption Function [PDF]

open access: yesSSRN Electronic Journal, 2008
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +4 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

General Approach to Function Approximation

open access: yesMathematics
Applying a predefined set of functionals to a function provides a set of numbers which characterize the function. One can then interpret an approximation very generally as a construction of some function form which reproduces these numbers if the same ...
Andrej Liptaj
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Modeling Point Source Potentials in Horizontally Layered Soils

open access: yesIEEE Access
This paper presents a novel model for electric current dissipation in horizontally stratified multilayer soils, applicable to arbitrary point source locations and evaluated at any spatial coordinate.
Rooney R. A. Coelho   +2 more
doaj   +1 more source

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