Results 81 to 90 of about 373,199 (312)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Efficient by Precision Algorithms for Approximating Functions from Some Classes by Fourier Series

open access: yesКібернетика та комп'ютерні технології
Introduction. The problem of approximation can be considered as the basis of computational methods, namely, the approximation of individual functions or classes of functions by functions that are in some sense simpler than the functions being ...
Olena Kolomys
doaj   +1 more source

Approximation by Step Functions [PDF]

open access: yesProceedings of the American Mathematical Society, 1963
i.e., of approximating a given matrix (aik) by a matrix of the particular type (Xi+yk), has proved to be very efficient. It is the "leveling process" [1; 2; 3] which roughly speaking for problem (1) consists in an alternatively repeated minimizing within the sets Ai (in problem (2) the rows and columns).
openaire   +1 more source

Spacetime: function and approximation

open access: yesSynthese, 2022
AbstractSeveral approaches to quantum gravity (QG) signal the loss of spacetime at some level. According to spacetime functionalism, spacetime is functionally realised by a more fundamental structure. According to one version of spacetime functionalism, the spacetime role is specified by Ramsifying general relativity (GR).
openaire   +3 more sources

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Optimal with Respect to Accuracy Recovery of Some Classes Functions by Fourier Series

open access: yesКібернетика та комп'ютерні технології
Introduction. Function approximation (approximation or restoration) is widely used in data analysis, model building, and forecasting. The goal of function approximation is to find the function that best approximates the original function.
Olena Kolomys
doaj   +1 more source

DISCRETE LEAST SQUARES APPROXIMATION OF PIECEWISE-LINEAR FUNCTIONS BY TRIGONOMETRIC POLYNOMIALS

open access: yesПроблемы анализа, 2017
Let N be a natural number greater than 1. Select N uniformly distributed points t_k = 2πk/N (0 ≤ k ≤ N − 1) on [0, 2π]. Denote by L_{n,N} (f) = L_{n,N} (f, x) (1 ≤ n ≤ N/2) the trigonometric polynomial of order n possessing the least quadratic deviation ...
G. G. Akniyev
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Measure Fields for Function Approximation

open access: yes, 1993
The computation of a piecewise smooth function that approximates a finite set of data points may be decomposed into two decoupled tasks: first, the computation of the locally smooth models, and hence, the segmentation of the data into classes that ...
Marroquin, Jose L.
core  

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